Efficacy of lidocaine wet compress combined with red-light irradiation for chronic wounds  

作　　者：Man-Zhen Bao Lian-Bang Zhou Ling Zhao Hui Zhang Yuan Li Li Yang An-Ting Tai 

机构地区：[1]Department of Nursing,The Second Affiliated Hospital of Anhui Medical University,Hefei 230601,Anhui Province,China [2]Department of General Surgery,The Second Affiliated Hospital of Anhui Medical University,Hefei 230601,Anhui Province,China [3]Department of General Surgery,Huaibei People’s Hospital of Anhui Province,Huaibei 235000,Anhui Province,China [4]Department of Outpatient,The Second Affiliated Hospital of Anhui Medical University,Hefei 230601,Anhui Province,China

出　　处：《World Journal of Clinical Cases》2023年第30期7277-7283,共7页世界临床病例杂志

基　　金：Supported by Scientific Research Fund of Anhui Medical University,No.2020xkj197.

摘　　要：BACKGROUND Chronic wounds that fail to progress through normal phases of healing present a significant healthcare burden owing to prolonged treatment and associated costs.Traditional wound care typically involves regular dressing changes,which can be painful.Recent approaches have explored the use of lidocaine to manage pain and red-light irradiation(RLI),known for its anti-inflammatory and cell proliferation effects,to potentially enhance wound healing.AIM To investigate the therapeutic efficacy of lidocaine wet compression(LWC)combined with RLI for chronic wounds.METHODS We enrolled 150 patients with chronic wounds from the Wound and Ostomy Outpatient Clinic of the Second Hospital of Anhui Medical University from April to September 2022.The wounds were treated with dressing changes.The patients were randomly assigned to the control and experimental groups using a random number table and given the same first dressing change(2%LWC for 5 min and routine dressing change).From the second dressing change,in addition to 2%LWC for 5 min and routine dressing change,the experimental group received RLI,whereas the control group continued to receive the same LWC and dressing change.The first and second dressing changes were performed on days 1 and 2,respectively.The third dressing change was performed 3 d after the second change.The frequency of subsequent dressing changes was determined based on wound exudation and pain.Pain during the first three dressing changes was evaluated in both groups.The average number of dressing changes within 28 d and the degree of wound healing on day 28 were also recorded.RESULTS During the initial dressing change,no noticeable differences were observed in the pain levels experienced by the two groups,indicating similar pain tolerance.However,during the second and third dressing changes,the experimental group reported significantly less pain than the control group.Furthermore,over 28 d,the experimental group required fewer dressing changes than the control group.CONCLUSION Notably,the effect

关 键 词：Chronic wound LIDOCAINE Red light PAIN Quality of Life Wound exudation 

分 类 号：R726.1[医药卫生—儿科]