再生丝素蛋白/聚乙烯醇共混取向纳米纤维膜的制备与性能  

Preparation and properties of regenerated silk fibroin/polyvinyl alcohol blended nanofiber membranes with predesigned orientation

作　　者：姚双双 付少举 张佩华[1,2] 孙秀丽[3] YAO Shuangshuang;FU Shaoju;ZHANG Peihua;SUN Xiuli(Key Laboratory of Textile Science&Technology,Ministry of Education,Donghua University,Shanghai201620,China;College of Textiles,Donghua University,Shanghai201620,China;Department of Gynaecology and Obstetrics,Peking University People′s Hospital,Beijing100044,China)

机构地区：[1]东华大学纺织面料技术教育部重点实验室,上海201620 [2]东华大学纺织学院,上海201620 [3]北京大学人民医院妇产科,北京100044

出　　处：《纺织学报》2023年第9期11-19,共9页Journal of Textile Research

基　　金：国家自然科学基金项目(82171615);高等学校学科创新引智计划资助项目(B07024)。

摘　　要：为进一步提升取向纳米纤维膜在纺织生物医学领域的应用潜力,以再生丝素蛋白(RSF)和聚乙烯醇(PVA)为原料,通过静电纺丝制备取向纳米纤维膜。通过单因子及正交试验确定最优纺丝参数,并对取向纳米纤维膜的形貌、化学结构、力学性能、热稳定性能等进行研究。结果表明:静电纺丝最优纺丝参数为选甲酸为溶剂,滚筒转速2400 r/min,纺丝液质量浓度0.16 g/mL,纺丝电压23 kV,出液速度0.6 mL/h,接收距离17 cm;RSF与PVA之间存在一定相互作用,使RSF中部分无规结构向α螺旋结构转变;与相同纺丝时间下得到的无取向纳米纤维膜相比,取向纳米纤维膜的特点为断裂强力更高,是无取向纳米纤维膜的2倍以上,孔径更大,集中在0.5μm附近;取向结构对纳米纤维膜热稳定性基本无影响。Objective Non-oriented nanofiber membranes are usually obtained on the receiving device due to instable movement of polymer jet in electrospinning.Oriented nanofiber membranes are obtained by changing the receiving device and other methods.Compared with non-oriented nanofiber membranes,oriented nanofiber membranes have the advantages of regular fiber arrangement and good mechanical properties.The paper proposes the preparation of oriented nanofiber membranes by electrospinning with regenerated silk fibroin(RSF)and polyvinyl alcohol(PVA)as raw materials,and potential applications of oriented nanofiber membranes in the field of textile biomedicine.Method The optimal spinning parameters were determined by single factor experiment and orthogonal experiment,and the morphology,chemical structure,mechanical properties,thermal stability,pore size distribution of oriented nanofiber membranes were studied with the assistance of scanning electron microscopes,Fourier transform infrared spectrometer,medical multi-function strength tester,synchronous thermal analyzer,and porous material pore size analyzer.Results Based on the nanofiber membrane morphology obtained from single factor experiment and orthogonal experiment(Fig.1,Tab.2 and Fig.2),it was evident that the optimal electrospinning parameters for preparing RSF/PVA blended oriented nanofiber membranes were as follows,formic acid as the solvent,roller speed of 2400 r/min,spinning fluid concentration of 0.16 g/mL,spinning voltage of 23 kV,outflow velocity of 0.6 mL/h,and receiving distance of 17 cm.Under these parameters,the oriented nanofiber membranes demonstrated regular morphology and high orientation(Fig.3 and Tab.3).It can be seen from the infrared spectra of RSF power,PVA grain and RSF/PVA oriented fiber membranes(Fig.4)that compared with RSF powder,part of amorphous structure in the oriented nanofiber membranes was transformed into theɑhelix structure.The stretching effect of the high-speed roller on the fiber was conductive to improving the degree of orientation

关 键 词：取向纳米纤维膜 静电纺丝 再生丝素蛋白 聚乙烯醇 

分 类 号：TS101.4[轻工技术与工程—纺织工程]