胺碘酮治疗急性心肌梗死后室性心律失常的临床疗效研讨  

Clinical Efficacy Study of Amiodarone in the Treatment of Ventricular Arrhythmia After Acute Myocardial Infarction

作　　者：康肖可 KANG Xiaoke(Department 2 of Internal Medicine,Linyi Lingang Economic Development Zone People's Hospital,Linyi 276600,China)

机构地区：[1]临沂临港经济开发区人民医院内二科,山东临沂276600

出　　处：《中国医药指南》2023年第30期45-48,共4页Guide of China Medicine

摘　　要：目的 探讨针对急性心肌梗死后室性心律失常的患者利用胺碘酮实行治疗的作用效果。方法 选取2021年12月至2022年12月在临沂临港经济开发区人民医院接受治疗的120例患有急性心肌梗死后室性心律失常患者为研究对象,依据治疗措施进行分组,每组各60例。参照组患者接受常规治疗,试验组患者接受胺碘酮治疗。观察两组患者治疗前后心电图指标、心功能指标、血清中N末端B型脑钠肽前体与肌钙蛋白水平、导尿管留置时间、心理状况评分、生活质量评分、术后住院时间、满意度评分、配合度评分、不良反应发生概率以及治疗效果,并进行对比。结果 试验组患者治疗后的各心电图指标优于参照组,组间数值比对有差异(P<0.05);与参照组相比较,试验组患者治疗后的各项心功能指标均较高,统计学软件比对后有意义(P<0.05);治疗后试验组患者的血清中N末端B型脑钠肽前体与肌钙蛋白水平低于参照组,数值分析具有统计学意义(P<0.05);与试验组相对比,参照组患者的导尿管留置时间、心理状况评分、生活质量评分、术后住院时间、满意度评分以及配合度评分均较差,经统计学软件比较后有意义(P<0.05);参照组患者不良反应发生率高于试验组,具有统计学有意义(P<0.05);试验组患者的临床治疗效果优于参照组,组间数值比对具有统计学意义(P<0.05)。结论 胺碘酮用于急性心肌梗死后室性心律失常的治疗,疗效明显,能够有效改善患者各项心电图指标、心功能指标,缓解血清中N末端B型脑钠肽前体与肌钙蛋白水平,降低不良反应发生概率。Objective To investigate the therapeutic effect of amiodarone on patients with ventricular arrhythmia after acute myocardial infarction.Methods 120 patients with ventricular arrhythmia after acute myocardial infarction who were treated in our hospital from December 2021 to December 2022 were selected as research subjects and grouped according to treatment measures,there were 60 cases in each group.Patients in the reference group received conventional treatment,and patients in the experimental group were given amiodarone treatment.Observe the electrocardiogram indexes,cardiac function indexes,serum levels of N-terminal B-type brain natriuretic peptide precursor and troponin,catheter indwelling time,psychological condition score,quality of life score,postoperative hospitalization time,satisfaction score,degree of cooperation score,the probability of occurrence of adverse reactions,and the therapeutic effects of the patients in the two groups before and after the treatment,and realize the comparison.Results The electrocardiographic indexes of patients in the experimental group were much better than those of the reference group after treatment,and the comparison of values between groups was statistically significant(P<0.05).The cardiac function indexes of patients in the experimental group were higher than those of the reference group after treatment,and there was significance in the comparison of the statistical software(P<0.05).The levels of serum N-terminal B-type brain natriuretic peptide precursor and troponin of the experimental group patients were much lower than that of the reference group,and the values of the experimental group patients were statistically significant(P<0.05).Compared with the experimental group,the catheter indwelling time,psychological condition score,quality of life score,postoperative hospitalization time,satisfaction score,and cooperation score of the reference group were worse,which was significant after comparison with statistical software(P<0.05).The probability of adverse reactions

关 键 词：胺碘酮 急性心肌梗死 室性心律失常 临床应用效果 

分 类 号：R542.22[医药卫生—心血管疾病] R541.7[医药卫生—内科学]