区域性动脉自旋标记技术在脑血管相关疾病中的研究进展  

Research progress of t-ASL in cerebrovascular related diseases

作　　者：刘蒋静 周智鹏[1] LIU Jiangjing;ZHOU Zhipeng(Department of Radiology,Affliatated Hospital of Guilin University,Guilin 541001,China)

机构地区：[1]桂林医学院附属医院放射科,桂林541001

出　　处：《磁共振成像》2023年第10期162-166,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金项目(编号:81760219)。

摘　　要：区域性动脉自旋标记(territorial arterial spin labeling, t-ASL)是一项新型磁共振灌注技术,通过选择性标记单支责任供血动脉,无须注射外源性对比剂就能有效评估颅内血管疾病中的责任供血动脉区域血流灌注情况。本文综述了t-ASL的技术原理及其在脑血管病、颅内肿瘤、非动脉硬化性脑病中的应用、局限性和未来发展方向,为进一步实现对颅内血管及非血管疾病患者的早期诊断、个体化治疗及预后方面提供了重要支持,为临床实践及科研提供了新思路、新方向。Territorial arterial spin labeling(t-ASL)is a novel magnetic resonance perfusion technique that effectively evaluates the regional blood flow perfusion of responsible blood supply arteries in intracranial vascular diseases by selectively labeling a single responsible blood supply artery without the need for injection of exogenous contrast agents.This article reviews the technical principles of t-ASL and its applications,limitations,and future development directions in cerebrovascular diseases,intracranial tumors,and non atherosclerotic encephalopathy.It provides important support for the early diagnosis,individualized treatment,and prognosis of patients with intracranial vascular and non vascular diseases,and provides new ideas and directions for clinical practice and research.

关 键 词：区域性动脉自旋标记 脑灌注成像 磁共振成像 缺血性脑卒中 烟雾病 动静脉畸形 脑膜瘤 非动脉硬化性脑病 责任供血动脉 侧支循环 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743[医药卫生—诊断学]