基于国产高端腔镜和新辅助治疗降期的支气管肺段袖式切除术临床效果评价  

Evaluation on the clinical effect of the resection of innovative sleeve type on bronchopulmonary segment based on domestically high-end endoscope and new adjuvant therapy at downstage

作　　者：吴子恒 王一青[1] 陈求名 夏平会 吕望[1] 李娜娜 冯靖祎[3,4] 胡坚 WU Zi-heng;WANG Yi-qing;CHEN Qiu-ming(Department of Generally Thoracic Surgery,The First Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310003,China;不详)

机构地区：[1]浙江大学医学院附属第一医院普胸外科,浙江杭州310003 [2]广东欧谱曼迪科技股份有限公司,广东佛山528200 [3]浙江大学医学院附属第一医院医学工程部,浙江杭州310003 [4]浙江省医疗器械临床评价技术研究重点实验室,浙江杭州310003

出　　处：《中国医学装备》2023年第10期20-23,共4页China Medical Equipment

基　　金：国家重点研发计划(2022YFC2407303)“肺部肿瘤精准根治技术国产高端腔镜系统与微创器械应用示范研究”;浙江省重点研发计划(2020C03058)“高端医学影像装备关键部件研发与系统集成-早期中央型肺癌筛查的国产支气管镜自主研发及应用”;浙江省教育厅科研项目资助(Y202250800)“自身抗体检测在肺癌筛查与监测中的临床价值研究”。

摘　　要：目的:探究基于国产高端腔镜和新辅助治疗降期的支气管肺段袖式切除术临床应用效果。方法:选取医院收治的20例新辅助治疗后行肺切除术的患者,按随机数表法将其分为观察组和对照组,每组10例。对照组予以传统肺叶切除术,观察组予以联合国产高端腔镜的支气管肺段袖式切除术,收集两组患者术中术后临床资料,并对两组患者围手术期指标和短期预后结果等进行统计分析。结果:观察组患者术后住院天数少于对照组,差异有统计学意义(Z=-1.991,P<0.05),术后并发症发生率均少于对照组,差异有统计学意义(x^(2)=7.200,P<0.05);观察组和对照组平均手术时间分别为(3.38±0.42)h和(2.61±0.33)h,其差异无统计学意义(t=1.445,P>0.05)。两组出血量和淋巴结清扫数比较,差异均无统计学意义(Z=-0.173,Z=-1.432;P>0.05)。结论:基于国产高端腔镜系统和新辅助治疗降期可以安全、有效地实行支气管肺段袖式切除等创新术式,发展、支持、应用国产高端腔镜系统有助于进一步实现肺部肿瘤微创术式创新。Objective:To explore the clinical application effect of resection of sleeve type on bronchopulmonary segment based on domestically high-end endoscope and new adjuvant therapy at downstage.Methods:A total of 20 patients who underwent pneumonectomy after new adjuvant therapy were selected and they were divided into observation group and control group according to random number table method,with 10 patients in each group.The control group received conventional lobectomy,while the observation group received the resection of sleeve type on bronchopulmonary segment that combined with domestic high-end endoscope.The clinical data of two groups were collected,and the perioperative indicators and short-term prognosis results were analyzed as statistical methods.Results:The hospitalization days after surgery in observation group was significantly less than that in control group,and the complications after surgery in observation group also was less than that in control group,with statistically significant differences(Z=-1.991,x^(2)=7.200,P<0.05),respectively.The operation times of observation group and control group were respectively(3.38±0.42)h and(2.61±0.33)h,without statistically significant difference between two groups(t=1.445,P>0.05).There were no statistically significant differences in the bleeding volume and the number of lymph node clearance(Z=-0.173,Z=-1.432,P>0.05).Conclusion:Based on the domestic high-end endoscopic system and the new adjuvant therapy at downstage,the innovatively surgical modes such as the resection of sleeve type on bronchopulmonary segment can be safely and effectively implemented.The development,support and application of domestic high-end endoscopic system will help to further realize the innovation of minimally invasive surgery for lung tumor.

关 键 词：支气管肺段 袖式切除 4K荧光 国产高端腔镜 免疫治疗 

分 类 号：R655.3[医药卫生—外科学]