一种基于类花菁检测过氧化氢荧光探针的合成  

Synthesis of a Hydrogen Peroxide Fluorescence Probe Based on Cyanine like Detection

作　　者：陈小宜 邓璇 樊辉 齐风佩 CHEN Xiaoyi;DENG Xuan;FAN Hui;QI Fengpei(College of Materials and Chemical Engineering,Hunan City University,Yiyang 413000,China)

机构地区：[1]湖南城市学院材料与化学工程学院,湖南益阳413000

出　　处：《工业微生物》2023年第5期19-22,共4页Industrial Microbiology

基　　金：湖南省教育厅优秀青年项目(20B104);湖南省教育厅优秀青年项目(21B0711);湖南省大学生创新创业项目(湘教通[2021]197号文件,3362号);湖南省自然科学基金省市联合基金项目(2022JJ50264)。

摘　　要：文章以2-甲基苯并噻唑和尼泊金乙酯为原料,合成了一种具有红色荧光的花菁类染料,该染料与4-溴甲基苯硼酸频哪醇酯反应可以生成用于检测过氧化氢的荧光探针。通过紫外和荧光研究该探针在不同溶剂、过氧化氢浓度、黏度条件下检测过氧化氢的响应。研究结果表明。在该实验中,过氧化氢浓度越高、体系黏度越低,探针荧光强度均逐渐降低,同时具有良好的选择性。A cyanine dye with red fluorescence was synthesized from 2-methyl Benzothiazole and ethyl paraben.The dye reacted with 4-bromomethyl Phenylboronic acid Pinacol ester to generate a fluorescent probe for the detection of hydrogen peroxide.The response of this probe to detecting hydrogen peroxide under different solvent,hydrogen peroxide concentration,and viscosity conditions was studied through UV and fluorescence.The research results indicate the higher the concentration of hydrogen peroxide,the lower the viscosity of the system,the fluorescence intensity of the probe decreases gradually,and the probe has good selectivity.

关 键 词：过氧化氢 花菁染料 荧光探针 苯并噻唑 

分 类 号：O657.3[理学—分析化学] R313[理学—化学]