蒿甲醚乳剂治疗肛周皮肤瘙痒症的疗效观察  

Efficacy of Artemether Emulsion in the Treatment of Perianal Skin Pruritus

作　　者：李淑[1] 沈文彤 何慧琼 裴琴 王国江 LI Shu;SHEN Wentong;HE Huiqiong;PEI Qin;WANG Guojiang(Department of Dermatology,Shanghai Jiading Hospital of Traditional Chinese Medicine,Shanghai 201899,China;Department of Dermatology,Zhou Pu Hospital Affiliated to Shanghai Health Medical College,Shanghai 201318,China)

机构地区：[1]上海市嘉定区中医医院皮肤科,上海201899 [2]上海健康医学院附属周浦医院皮肤科,上海201318

出　　处：《皮肤科学通报》2023年第4期505-508,共4页Dermatology Bulletin

基　　金：上海市浦东新区优秀青年医学人才培养项目(PWRQ2020-39)。

摘　　要：目的观察蒿甲醚乳剂治疗肛周皮肤瘙痒症的临床疗效。方法将符合诊断标准的60例肛周皮肤瘙痒症患者随机分为治疗组和对照组,每组各30例,治疗组应用蒿甲醚乳剂,对照组应用他克莫司软膏。比较两组患者的临床疗效及半年内的复发率情况,并评价两组的安全性。结果治疗2周后,治疗组有效率为83.33%,对照组有效率为86.67%,两组疗效相当(P>0.05);疗程结束后3个月复发率比较,两组差异无统计学意义(P>0.05),疗程结束后6个月复发率比较,两组差异有统计学意义(P<0.05)。结论蒿甲醚乳剂治疗肛周皮肤瘙痒症安全有效,副作用小,且复发率低。Objective To observe the clinical efficacy of artemether emulsion in the treatment of perianal skin pruritus.Methods Sixty cases of anal pruritus were randomly divided into observation group and control group,30 cases in each group.The treatment group was given artemether emulsion and the control group with tacrolimus ointment.The clinical efficacy and recurrence rate within half a year were compared between the two groups,and the safety of the two groups was evaluated.Results After two weeks of treatment,the effective rate was 83.33% in the treatment group and 86.67% in the control group,the two groups were equal(P0.05).There was no significant difference between the two groups in the recurrence rate after 3 months(P0.05).There were significant differences between the two groups in the recurrence rate 6 months after treatment(P0.05).Conclusion Artemether emulsion is safe and effective in the treatment of perianal pruritus,with few side effects and low recurrence rate.

关 键 词：蒿甲醚乳剂 肛周皮肤瘙痒症 他克莫司软膏 临床疗效 复发率 

分 类 号：R758.31[医药卫生—皮肤病学与性病学]