儿科常用H_(1)抗组胺药处方审核专家共识  

Consensus on prescription review of commonly used H_(1)-antihistamines in pediatrics

作　　者：胡利华[1] 刘璐[2] 陈慧颖 蔡和平 葛文彤[4] 韩志英[5] 皇惠杰 季兴[7] 贾运涛[8] 菅凌燕[9] 姜楠楠 李中 李莉[11] 梁华 刘传合[13] 卢庆红[14] 卢旭 马俊娥 缪静 任艳丽[18] 尚云晓[19] 申昆玲[20] 孙华君 孙金峤 孙燕燕[23] 汤建萍[24] 王红 王良录[25] 王晓川 喜雷 徐华[26] 徐子刚[27] 闫美兴 殷勇[28] 张胜男 张中平[30] 赵昕[31] 赵德育[32] 周薇[33] 向莉[6] 王晓玲[1] Hu Lihua;Liu Lu;Chen Huiying;Cai Heping;Ge Wentong;Han Zhiying;Huang Huijie;Ji Xing;Jia Yuntao;Jian Lingyan;Jiang Nannan;Li Zhong;Li Li;Liang Hua;Liu Chuanhe;Lu Qinghong;Lu Xu;Ma Jun′e;Miao Jing;Ren Yanli;Shang Yunxiao;Shen Kunling;Sun Huajun;Sun Jinqiao;Sun Yanyan;Tang Jianping;Wang Hong;Wang Lianglu;Wang Xiaochuan;Xi Lei;Xu Hua;Xu Zigang;Yan Meixing;Yin Yong;Zhang Shengnan;Zhang Zhongping;Zhao Xin;Zhao Deyu;Zhou Wei;Xiang Li;Wang Xiaoling(Department of Pharmacy,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Department of Pharmacy,Women and Children′s Hospital,Qingdao University,Qingdao 266034,China;Department of Clinical Pharmacy,Anhui Children′s Hospital,Hefei 230022,China;Department of Otorhinolaryngology Head and Neck Surgery,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Department of Respiratory,Shanxi Children′s Hospital,Taiyuan 300013,China;Department of Allergy,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Department of Pharmacy,Children′s Hospital of Nanjing Medical University,Nanjing 210008,China;Department of Pharmacy,Children′s Hospital of Chongqing Medical University,Chongqing 400014,China;Department of Pharmacy,Shengjing Hospital of China Medical University,Shenyang 110004,China;Department of Pharmacy,Dalian Women and Children′s Medical Group,Dalian 116011,China;Department of Ophthalmology,Beijing Children′s Hospital,Capital Medical University,National Center for Children′s Health,Beijing 100045,China;Department of Pharmacy,Chengdu Women′s and Children′s Central Hospital,Chengdu 611731,China;Department of Allergy,Children′s Hospital Affiliated to Capital Institute of Pediatrics,Beijing 100020,China;Department of Pharmacy,Jiangxi Provincial Children′s Hospital,Nanchang 330006,China;Department of Pediatrics,Beijing Tongzhou District Maternal and Child Health Care

机构地区：[1]国家儿童医学中心,首都医科大学附属北京儿童医院药学部,北京100045 [2]青岛大学附属妇女儿童医院药学部,青岛266034 [3]安徽省儿童医院临床药学部,合肥230022 [4]国家儿童医学中心,首都医科大学附属北京儿童医院耳鼻咽喉头颈外科,北京100045 [5]山西省儿童医院呼吸科,太原300013 [6]国家儿童医学中心,首都医科大学附属北京儿童医院过敏反应科,北京100045 [7]南京医科大学附属儿童医院药学部,南京210008 [8]重庆医科大学附属儿童医院药学部,重庆400014 [9]中国医科大学附属盛京医院药学部,沈阳110004 [10]大连市妇女儿童医疗中心(集团)药剂科,大连116011 [11]国家儿童医学中心,首都医科大学附属北京儿童医院眼科,北京100045 [12]成都市妇女儿童中心医院药学部,成都611731 [13]首都儿科研究所附属儿童医院变态反应科,北京100020 [14]江西省儿童医院药学部,南昌330006 [15]北京市通州区妇幼保健院儿科,北京101100 [16]民航总医院儿科,北京100123 [17]浙江大学医学院附属儿童医院药剂科,杭州310052 [18]郑州大学第三附属医院药学部,郑州450052 [19]中国医科大学附属盛京医院小儿呼吸内科,沈阳110004 [20]国家儿童医学中心,国家呼吸系统疾病临床医学研究中心,首都医科大学附属北京儿童医院呼吸科,北京100045 [21]上海市儿童医院,上海交通大学医学院附属儿童医院药学部,上海200062 [22]国家儿童医学中心,复旦大学附属儿科医院临床免疫科,上海201102 [23]天津市儿童医院药剂科,天津300134 [24]湖南省儿童医院皮肤科,长沙410007 [25]北京协和医院变态反应科,北京100730 [26]华中科技大学同济医学院附属武汉儿童医院药学部,武汉430019 [27]国家儿童医学中心,首都医科大学附属北京儿童医院皮肤科,北京100045 [28]国家儿童医学中心,上海交通大学医学院附属上海儿童医学中心呼吸内科,上海200127 [29]河�

出　　处：《中华实用儿科临床杂志》2023年第10期733-739,共7页Chinese Journal of Applied Clinical Pediatrics

基　　金：儿童过敏性哮喘治疗药物研究及用药体系建设(HXZX-202107)。

摘　　要：H_(1)抗组胺药广泛用于各种过敏性疾病的治疗,但在儿科的安全合理应用仍存在诸多挑战,且缺乏专门针对儿童使用H_(1)抗组胺药的处方审核相关的指导文件。现从H_(1)抗组胺药在儿科使用的适应证、剂量、给药途径、患儿的病理生理特性以及药物相互作用等方面提出建议,制定本共识,供临床医师和药师参考。H_(1)-antihistamines are widely used in the treatment of various allergic diseases,but there are still many challenges in the safe and rational use of H_(1)-antihistamines in pediatrics,and there is a lack of guidance on the prescription review of H_(1)-antihistamines for children.In this paper,suggestions are put forward from the indications,dosage,route of administration,pathophysiological characteristics of children with individual difference and drug interactions,so as to provide reference for clinicians and pharmacists.

关 键 词：H_(1)抗组胺药 儿童 过敏性疾病 处方审核 专家共识 

分 类 号：R95[医药卫生—药学]