盆炎方联合宫腹腔镜手术对输卵管阻塞性不孕患者的疗效  

Effect of Penyanfang combined with hysteroscopy and laparoscopy in patients with tubal obstructive infertility

作　　者：吴晓雁 方培婉 林纯洁 陈思思 杨燕贤 WU Xiao-yan;FANG Pei-wan;LIN Chun-jie;CHEN Si-si;YANG Yan-xian(Shantou Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine,Shantou 515041;Medical College of Foshan University of Science and Technology,Foshan 528000;Department of Gynaecology,Shantou Hospital of Traditional Chinese Medicine,Shantou 515041,Guangdong,China)

机构地区：[1]广州中医药大学附属汕头中医院,广东汕头515041 [2]佛山科学技术学院医学院,广东佛山528000 [3]汕头市中医医院妇科,广东汕头515041

出　　处：《川北医学院学报》2023年第10期1375-1378,共4页Journal of North Sichuan Medical College

基　　金：广东省汕头市科技计划医疗卫生类项目(180806214012305)。

摘　　要：目的:探讨盆炎方联合宫腹腔镜手术对输卵管阻塞性不孕(TOF)患者的疗效及对血液流变学和血清炎症因子的影响。方法:选择160例TOF患者为研究对象,根据治疗方案不同分为西医组(n=80)与中西医组(n=80)。西医组予以宫腹腔镜手术;中西医组予以盆炎方联合宫腹腔镜手术治疗。3个月后进行疗效评价,比较两组患者输卵管再通率、症状评分、血液流变学[血浆黏度、红细胞比容(Hct)、血沉(ESR)]和血清炎症因子[降钙素原(PCT)、C反应蛋白(CRP)]变化。随访6个月,比较两组妊娠情况。结果:中西医组输卵管再通率为73.75%,高于西医组的57.50%(P<0.05)。治疗后,中西医组中医证候积分和局部体征评分低于西医组(P<0.05)。治疗后,中西医组血浆黏度、Hct、ESR和PCT、CRP水平均低于西医组(P<0.05)。随访6个月,中西医组妊娠率为37.50%,高于西医组的22.50%,差异有统计学意义(P<0.05)。结论:对于TOF,盆炎方联合宫腹腔镜手术治疗能够调节血液流变,减轻炎症反应,提高输卵管再通率,促进妊娠。Objective:To investigate the effect of Penyan Decoction combined with hysteroscopy and laparoscopy on tubal obstructive infertility and its influence on hemorheology and serum inflammatory factors.Methods:160 patients with TOF were collected and divided into Western medicine group(n=80)and Chinese and Western medicine group(n=80)according to different treatment schemes.The Western medicine group was given hysteroscopic and laparoscopic surgery,Chinese and Western medicine group to pelvic inflammatory combined hysteroscopic and laparoscopic surgery.The curative effect was evaluated after 3 months.The fallopian tube recanalization rate,symptom score,hemorheology[plasma viscosity,hematocrit(Hct),erythrocyte sedimentation rate(ESR)]and inflammatory factors[procalcitonin(PCT),C-reactive protein(CRP)]were compared between the two groups,and the pregnancy of the two groups was compared after 6 months of follow-up.Results:The fallopian tube recanalization rate of the Chinese and Western medicine group was 73.75%,which was higher than 57.50% of the Western medicine group(P<0.05).After treatment,the scores of TCM syndromes and local signs in the Chinese and Western medicine group were lower than those in the Western medicine group(P<0.05).After treatment,the levels of plasma viscosity,Hct,ESR,PCT and CRP in the Chinese and Western medicine group were lower than those in the Western medicine group(P<0.05).After 6 months of follow-up,the pregnancy rate of the Chinese and Western medicine group was 37.50%,which was higher than 22.50% of the Western medicine group,the difference was statistically significant(P<0.05).Conclusion:For TOF,Penyan Decoction combined with hysteroscopy and laparoscopy can regulate blood rheology,reduce inflammatory reaction,improve fallopian tube recanalization rate and promote pregnancy.

关 键 词：输卵管阻塞性不孕 宫腹腔镜手术 血液流变学 炎症反应 妊娠 

分 类 号：R713.7[医药卫生—妇产科学]