1990—2019年江苏省甲状腺癌疾病负担及时间趋势分析  

Disease burden and trends of thyroid carcinoma in Jiangsu Province,1990-2019

作　　者：李伟伟[1] 董建梅[1] 秦绪成[1] 马昭君[1] 韩仁强[2] 俞浩[2] LI Weiwei;DONG Jianmei;QIN Xucheng;MA Zhaojun;HAN Renqiang;YU Hao(Lianyungang Center for Disease Control and Prevention,Lianyungang 222003,China;Jiangsu Provincial Center for Disease Control and Prevention)

机构地区：[1]连云港市疾病预防控制中心,江苏连云港222003 [2]江苏省疾病预防控制中心

出　　处：《华南预防医学》2023年第7期808-812,共5页South China Journal of Preventive Medicine

基　　金：江苏省卫生计生委预防医学科研课题(Y2015030)。

摘　　要：目的分析1990—2019年江苏省甲状腺癌患病率、发病率、死亡率和伤残调整生命年(disability adjusted life years,DALYs)情况及其变化趋势。方法基于2019年全球疾病负担研究(GBD 2019)数据,对1990—2019年江苏省甲状腺癌的标化患病率、发病率、死亡率和DALYs率进行描述分析,用Joinpoint软件对其标化率进行趋势分析,计算平均年度变化百分比(average annual percentage change,AAPC)。结果1990—2019年江苏省甲状腺癌标化患病率由5.22/10万增至14.68/10万,标化发病率由0.84/10万增至1.80/10万,标化死亡率由0.35/10万减至0.28/10万,标化DALYs率由8.34/10万减至6.91/10万。甲状腺癌的标化患病率(AAPC=3.6%,P<0.05)和标化发病率(AAPC=2.9%,P<0.05)总体呈上升趋势,分性别趋势方向一致,男性增长趋势高于女性。标化死亡率(AAPC=-0.9%,P<0.05)和标化DALYs率(AAPC=-0.6%,P<0.05)总体呈下降趋势,女性趋势方向与总体一致,但男性呈上升趋势。结论1990—2019年江苏省甲状腺癌标化患病率和标化发病率呈增长趋势,标化死亡率和标化DALYs率呈下降趋势,男性标化患病率、标化发病率、标化死亡率和标化DALYs率均呈增长趋势,应予以重点关注。Objective To analyze the prevalence,morbidity,mortality,and disability adjusted life years(DALYs)of thyroid carcinoma in Jiangsu Province from 1990 to 2019 and their trends.Methods The standardized prevalence,morbidity,mortality,and DALYs rate of thyroid carcinoma in Jiangsu Province from 1990 to 2019 were analyzed which were based on 2019 Global Burden of Disease Study(GBD 2019)database.Joinpoint software was used to analyze the trend of standardized rate and calculate the average annual percentage change(AAPC).Results From 1990 to 2019 in Jiangsu Province,the standardized prevalence of thyroid carcinoma increased from 5.22/105 to 14.68/105,the standardized morbidity increased from 0.84/105 to 1.80/105,the standardized mortality decreased from 0.35/105 to 0.28/105,and the standardized DALYs rate decreased from 8.34/105 to 6.91/105.The standardized prevalence and morbidity showed an upward trend(AAPC=3.6%,P<0.05;AAPC=2.9%,P<0.05),the rising trends were showed in both females and males,males were higher than females.The standardized mortality and DALYs rate showed a downward trend in whole population(AAPC=-0.9%,P<0.05;AAPC=-0.6%,P<0.05),females were as same as the whole population,but males were opposite which were still increasing.Conclusions From 1990 to 2019 in Jiangsu Province,the standardized prevalence and morbidity of thyroid carcinoma were on the rise,while the standardized mortality and DALYs rate had been falling.The standardized prevalence,morbidity,mortality,and DALYs rate of male patients all demonstrated the rising trends,which should be paid more attention to.

关 键 词：甲状腺癌 疾病负担 患病率 发病率 死亡率 

分 类 号：R195[医药卫生—卫生统计学]