按摩推拿对妊娠剧吐干预有效性的系统评价与Meta分析  

Systematic review and meta-analysis of the effectiveness of massage and tuina on hperemesis gravidarum

作　　者：李一凡 杨光奕 杨馥璟 官庆烨 徐博坦 梁笑语 李可[1] LI Yifan;YANG Guangyi;YANG Fujing;GUAN Qingye;XU Botan;LIANG Xiaoyu;LI Ke(School of Acupuncture-Moxibustion and Tuina,Beijing University of Chinese Medicine,Beijing 100029,China;School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China;School of Nursing,Beijing University of Chinese Medicine,Beijing 100029,China;Qi-Huang Chinese Medicine School,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学针灸推拿学院,北京100029 [2]北京中医药大学中医学院,北京100029 [3]北京中医药大学护理学院,北京100029 [4]北京中医药大学岐黄学院,北京100029

出　　处：《济宁医学院学报》2023年第5期353-358,共6页Journal of Jining Medical University

摘　　要：目的系统评价按摩推拿临床治疗妊娠剧吐的有效性。方法通过计算机检索中国生物医学文献数据库(Sino Med)、中国期刊全文数据库(CNKI)、万方学术期刊全文数据库(Wan fang Data)、维普中文科技期刊数据库(VIP)、PubMed、荷兰医学文献数据库(Embase)、Cochrane图书馆(The Cochrane Library)7个数据库。检索数据库建库以来至2023年6月30日。收集运用按摩推拿治疗妊娠剧吐的随机对照试验研究,对纳入病例进行数据提取和方法学质量评价。运用RevMan 5.3进行Meta分析合并效应量,用漏斗图分析发表偏倚,Egger′s检验。结果共纳入文献17篇,样本量1439例,其中干预组721例,对照组718例。Meta分析结果显示按摩推拿或按摩推拿联合其他疗法能提高治疗总有效率[OR=4.69,95%CI(3.29~6.69),Z=8.54,P<0.001]、加快尿酮体转阴时间[MD=-1.06,95%CI(-1.96~-0.17),Z=2.32,P=0.02]、缩短住院天数[MD=-2.55,95%CI(-4.30~-0.80),Z=2.85,P=0.004]、提高护理满意度[OR=6.85,95%CI(3.12~15.03),Z=4.80,P<0.001]。结论按摩推拿对改善妊娠剧吐作用显著,将来需要更多大样本、高质量的随机对照临床试验来证明结论的可靠性。Objective To systematically review the efficacy of massage and Tuina in the treatment of hyperemesis gravidarum.Methods Seven databases including Sino Med,CNKI,Wanfang Data,VIP,PubMed,Embase and The Cochrane Library were searched by computer from inception to June 30,2023.Randomized controlled trials(RCTs)of massage and tuina for hyperemesis gravidarum were collected.Included RCTs were conducted assessed data extraction and quality assessment.Meta-analysis was performed using RevMan 5.3 software,publication bias was analyzed by funnel plot and the result was assessed by Egger′s.Results A total of 17 RCTs were included,with a sample size of 1439 cases,including 721 cases in the intervention group and 718 cases in the control group.Meta-analysis was performed on the total clinical effective rate[OR=4.69,95%CI(3.29~6.69),Z=8.54,P<0.001],urine ketone body negative time[MD=-1.0695%CI(-1.96~-0.17),Z=2.32,P=0.02]hospitalization days[MD=-2.55,95%CI(-4.30~-0.80),Z=2.85,P=0.004]and nursing satisfaction[OR=6.85,95%CI(3.12~15.03),Z=4.80,P<0.001].Conclusion Current evidence shows that massage and Tuina therapy has advantages in the treatment of hyperemesis gravidarum,which needs to be proved by more large-sample,high-quality randomized controlled clinical trials.

关 键 词：按摩 推拿 妊娠剧吐 META分析 随机对照试验 

分 类 号：R714[医药卫生—妇产科学]