中西医调控肠道菌群干预老年桥本甲状腺炎的研究进展  

Research progress of regulation of intestinal flora by Chinese and western medicine in the intervention of Hashimoto thyroiditis in the elderly

作　　者：柏玉卓 张怡雯 吴大龙[1] BAI Yuzhuo;ZHANG Yiwen;WU Dalong(Affiliated Hospital of Changchun University of Chinese Medicine,Changchun130000,China)

机构地区：[1]长春中医药大学附属医院,长春130021

出　　处：《吉林中医药》2023年第10期1233-1236,共4页Jilin Journal of Chinese Medicine

基　　金：吉林省中医药科技项目(2019074)。

摘　　要：慢性淋巴细胞性甲状腺炎又称桥本氏甲状腺炎(Hashimoto thyroiditis,HT)是目前最常见的自身免疫性甲状腺疾病(autoimmune thyroiditis,AITD),是引起甲减的常见原因。微生物群-肠道-甲状腺轴的确立及研究表明HT的发生和发展可能因肠道微生物组成的变化或明显的菌群失调而受到显著影响,随着年龄增长,老年人肠道菌群结构和功能发生相应改变。这提示肠道菌群失调可能对老年人HT有更大的影响。本文就老年人肠道菌群改变、桥本甲状腺炎肠道菌群特征,以及中、西医调控方式进行简要综述,旨在为临床对桥本甲状腺炎的针对性防治及治疗提供最新的见解。Chronic lymphocytic thyroiditis,also known as Hashimoto thyroiditis(HT),is currently the most common autoimmune thyroid disease(AITD)and a common cause of hypothyroidism.The establishment and study of the microbiome-gut-thyroid axis indicate that the occurrence and development of HT may be significantly affected by changes in the intestinal microbiome composition or obvious dysbiosis,and the structure and function of intestinal microbiome in the elderly may change accordingly with the increase of age,suggesting that the imbalance of intestinal flora may have a greater impact on HT in the elderly.This article briefly reviews the changes of intestinal flora in the elderly,the characteristics of intestinal flora in patients with Hashimoto thyroiditis,and the regulation of intestinal flora in patients with Hashimoto thyroiditis in Chinese medicine and western medicine,aiming at providing the latest insights for the targeted prevention and treatment of the disease in clinical practice.

关 键 词：桥本甲状腺炎 肠道菌群 中西医治疗 

分 类 号：R581.4[医药卫生—内分泌]