社区老年心房颤动患者非卒中性认知功能障碍影响因素分析  

Analysis of the influence factors of non-stroke cognitive dysfunction in elderly patients with atrial fibrillation in the community

作　　者：谢样俊 龚辉 XIE Yangjun;GONG Hui(Department of General Practice of Jinshanwei Community Health Service Center of Jinshan District,Shanghai 201512,China;Department of Cardiovascular Medicine of Jinshan Hospital Affiliated to Fudan University,Shanghai 201508,China)

机构地区：[1]上海市金山区金山卫镇社区卫生服务中心全科,上海201512 [2]复旦大学附属金山医院心血管内科,上海201508

出　　处：《上海医药》2023年第20期42-46,共5页Shanghai Medical & Pharmaceutical Journal

基　　金：上海市金山区卫生健康委员会科研课题(JSKJ-KTSQ-2019-05)。

摘　　要：目的:探讨社区老年心房颤动(简称房颤)患者非卒中性认知功能障碍的相关影响因素。方法:连续纳入2020-2021年在金山卫镇参加60岁及以上老年体检的房颤患者143例,其中男性90例,女性53例。通过简易精神状态评价量表(MMSE)评估其认知功能,并分为认知功能正常组和认知功能障碍组,分析研究对象的相关因素与认知功能的关系。结果:二元Logistic回归分析显示:年龄(OR=1.095,95%CI:1.012~1.185,P=0.024)、收缩压(OR=0.948,95%CI:0.913~0.983,P=0.004)、冠心病(OR=2.736,95%CI:1.014~7.385,P=0.047)、红细胞分布宽度(OR=1.831,95%CI:1.730~1.946,P=0.005)、控制心室率治疗(OR=0.238,95%CI:0.085~0.666,P=0.006)是影响房颤患者认知功能障碍的因素。结论:房颤是认知功能障碍的独立危险因素。收缩压及控制心室率治疗是房颤患者发生认知功能障碍的保护因素,而年龄、红细胞分布宽度和冠心病是危险因素。Objective:To explore the related influence factors of non-stroke cognitive dysfunction in elderly patients with atrial fibrillation in the community.Methods:A total of 143 elderly patients aged above 60 years with atrial fibrillation who participated in physical examination in Jinshanwei Community from 2020 to 2021 were continuously included in the study,among them there were 90 male cases and 53 female cases.The cognitive function was assessed by mini-mental state examination assessment scale(MMSE),and the patients were divided into a normal cognitive function group and a disabled cognitive function group,and correlation of related factors and cognitive function of the research objects were analyzed.Results:Binary logistic regression analysis showed that:Age(OR=1.095,95%CI:1.012-1.185,P=0.024),systolic blood pressure(OR=0.948,95%CI:0.913-0.983,P=0.004),coronary heart disease(OR=2.736,95%CI:1.014-7.385,P=0.047),erythrocyte distribution width(OR=1.831,95%CI:1.730-1.946,P=0.005),control ventricular rate therapy(OR=0.238,95%CI:0.085-0.666,P=0.006)were the influencing factors of cognitive dysfunction.Conclusion:Atrial fibrillation is an independent risk factor for cognitive dysfunction.Systolic blood pressure and treatment for controlling ventricular rate are protective factors for cognitive dysfunction in patients with atrial fibrillation,while age,erythrocyte distribution width and coronary heart disease are the risk factors.

关 键 词：心房颤动 认知功能 影响因素 社区 老年人 

分 类 号：R541.75[医药卫生—心血管疾病]