Metal-free synthesis of nitriles from aldehydes and ammonium by visible-light photocatalysis  

作　　者：Xu He Yi-Wen Zheng Bin Chen Ke Feng Chen-Ho Tung Li-Zhu Wu 

机构地区：[1]Key Laboratory of Photochemical Conversion and Optoelectronic Materials,New Cornerstone Science Laboratory,Technical Institute of Physics and Chemistry,Chinese Academy of Sciences,Beijing 100190,China [2]School of Future Technology,University of Chinese Academy of Sciences,Beijing 100049,China [3]BayRay Innovation Center,Shenzhen Bay Laboratory,Shenzhen 518107,China

出　　处：《Science China Chemistry》2023年第10期2852-2857,共6页中国科学（化学英文版）

基　　金：supported by the National Key R&D Program of China(2021YFA1500100,2022YFA1502900);the National Natural Science Foundation of China(21933007,22193013,22088102);the Strategic Priority Research Program of the Chinese Academy of Science(XDB17000000);New Cornerstone Science Foundation。

摘　　要：A green method for synthesis of nitriles from aldehydes and ammonium salts under air is developed under extremely mild conditions,i.e.,1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene(4Cz IPN)as a photocatalyst,2,2,6,6-tetrametylpiperidine-1-oxyl(TEMPO)as a cocatalyst,and oxygen(ambient air)as the terminal oxidant,visible light irradiation of substrate solutions,producing the desired nitriles with excellent yields.The reaction involves two distinct transformations,imine formation between an aldehyde and an ammonium salt and photocatalytic oxidation of the formed imine by air to a nitrile.

关 键 词：visible-light photocatalysis ALDEHYDES NITRILES METAL-FREE ambient air 

分 类 号：O623.76[理学—有机化学]