实脾五皮饮对心力衰竭血清N-端脑钠肽前体水平的影响  

Effect of Shipi Wupi Drink on Level of Serum N-terminal pro-brain Natriuretic Peptide in Patients with Heart Failure

作　　者：杨窑莉 李川[1] YANG Yaoli;LI Chuan(Department of Internal Medicine,Nanchang Hongdu Hospital of Traditional Chinese Medicine,Jiangxi Province,Nanchang 330000,China)

机构地区：[1]南昌市洪都中医院内三科,江西南昌330000

出　　处：《中国中医药现代远程教育》2023年第22期83-85,共3页Chinese Medicine Modern Distance Education of China

基　　金：江西省中医药管理局科技计划课题【No.2020A0037】。

摘　　要：目的观察实脾五皮饮对心力衰竭血清N-端脑钠肽前体(NT-proBNP)水平的影响。方法将74例符合纳入标准的患者随机分成对照组和治疗组,各37例。对照组给予常规西药治疗,治疗组在常规治疗基础上加用实脾五皮饮,观察治疗前、治疗后2周、治疗后4周NT-proBNP变化情况。结果治疗后,治疗组各时间段NT-proBNP水平低于对照组(P<0.05);治疗组总有效率为97.30%(36/37),高于对照组的91.89%(34/37),差异有统计学意义(P<0.05)。结论在常规治疗基础上加用实脾五皮饮的临床效果好,可明显改善NT-proBNP水平,且治疗期间,患者配合性好,不良反应发生率低,值得临床推广。Objective To observe the clinical effect of Shipi Wupi drink on the level of serum N-terminal pro-brain natriuretic peptide(NT-probNP)in heart failure.Methods Seventy-four patients who met the inclusion criteria were randomly divided into control group and treatment group,with 37 cases in each group.The control group was treated with conventional Western medicine,and the treatment group was treated with Shipi Wupi drink on the basis of conventional treatment.The changes of NT-proBNP before treatment,2 weeks after treatment and 4 weeks after treatment were observed.Results After treatment,the level of NT-proBNP in the treatment group was lower than that in the control group(P<0.05).The total effective rate of the treatment group was 97.30%(36/37),which was higher than that of the control group(91.89%,34/37),and the difference was statistically significant(P<0.05).Conclusion On the basis of conventional treatment,the addition of Shipi Wupi drink has good clinical effect,which can significantly improve the level of NT-proBNP,and during treatment,patients have good cooperation and low incidence of adverse reactions,which is worthy of clinical promotion.

关 键 词：心力衰竭 N-端脑钠肽前体 实脾五皮饮 中医药疗法 

分 类 号：R259[医药卫生—中西医结合]