中药防治糖尿病肾病实验研究进展  

Progress of experimental research on prevention and treatment of diabetic kidney disease by traditional Chinese medicine

作　　者：朱栎娟 杨杰[1] 闻晓东[1] 周珂[2] ZHU Lijuan;YANG Jie;WEN Xiaodong;ZHOU Ke(State Key Laboratory of Natural Medicines,School of Traditional Chinese Medicine,China Pharmaceutical University,Nanjing 211198;Department of Nephrology and Endocrinology,Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha 410005,China)

机构地区：[1]中国药科大学中药学院,天然药物活性组分与药效国家重点实验室,南京211198 [2]湖南中医药大学第二附属医院肾病内分泌科,长沙410005

出　　处：《中国药科大学学报》2023年第5期644-652,共9页Journal of China Pharmaceutical University

基　　金：国家重点研发计划资助项目(No.2018YFC1704503)。

摘　　要：糖尿病肾病(diabetic kidney disease,DKD)是糖尿病严重的并发症之一,也是导致终末期肾病(end-stage renal disease,ESRD)发生的重要因素。DKD主要临床表现为白蛋白尿和肾小球滤过率下降,严重影响了患者的生活质量,并带来巨大的经济负担。中药(traditional Chinese medicine,TCM)在治疗糖尿病肾病中积累了丰富的经验。本文从中药成分、药对、中药复方3个方面对近年来中药治疗DKD的研究进展进行分析总结,以期为广大研究者实验研究提供新思路。Diabetic kidney disease(DKD)is one of the main complications of diabetes,and also the leading cause of the end-stage renal disease(ESRD).The main clinical manifestations are albuminuria and decreased glomerular filtration rate.DKD seriously affects the quality of life of sufferers and places a huge financial burden on them.Traditional Chinese medicine(TCM)has accumulated rich experience in treating DKD.This paper analyzed and summarized the recent treatment of DKD with traditional Chinese medicine from three aspects:active ingredients of TCM,TCM pairs and TCM prescriptions,so as to provide new ideas for the majority of researchers in experimental research.

关 键 词：糖尿病肾病 中药活性成分 中药药对 中药复方 

分 类 号：R285.6[医药卫生—中药学] R692[医药卫生—中医学]