维持性血液透析患者住院的影响因素分析  

Analysis of influencing factors of hospitalization in maintenance hemodialysis patients

作　　者：李婷[1] 王秀峰 赵玉杰 关林萌 邵晓琳 王辉[1] 杨军[1] LI Ting;WANG Xiufeng;ZHAO Yujie;GUAN Linmeng;SHAO Xiaolin;WANG Hui;YANG Jun(Blood purification Department,The First Affiliated Hospital of Xinxiang Medical University,Weihui Henan 453100,China;Department of Hematology,The First Affiliated Hospital of Xinxiang Medical University,Weihui Henan 453100,China)

机构地区：[1]新乡医学院第一附属医院血液净化室,河南卫辉453100 [2]新乡医学院第一附属医院血液内科,河南卫辉453100

出　　处：《中国临床医生杂志》2023年第11期1305-1308,共4页Chinese Journal For Clinicians

基　　金：河南省医学科技攻关计划项目(LHGJ20220590);新乡医学院第一附属医院青年培育基金项目(QN-2020-B06)。

摘　　要：目的探讨维持性血液透析(maintenance hemodialysis,MHD)患者住院的影响因素。方法选取2020年1月至2020年6月在新乡医学院第一附属医院血液净化中心行规律血液透析且病情稳定的门诊患者156例,根据促红细胞生成素抵抗指数(erythropoietin resistance index,ERI)中位数[18.80U·L/(kg·g)]分为高ERI组和低ERI组,各78例,随访24个月,比较两组患者住院率的差异及MHD患者住院的影响因素。结果患者住院率与ERI、年龄、透析间期体重增长、超敏C反应蛋白呈正相关,与白蛋白、血磷、透前舒张压呈负相关。多因素logistic回归分析结果显示,年龄和ERI是MHD患者住院的独立影响因素。KaplanMeier生存分析显示高ERI组的住院率明显高于低ERI组,差异有显著性(P<0.001)。结论ERI和年龄是MHD患者住院率增加的独立危险因素,高ERI和高龄的透析患者更容易因各种并发症进行住院治疗。Objective To explore the influencing factors of hospitalization in maintenance hemodialysis(MHD)patients.Methods MHD patients undergoing hemodialysis in The First Affiliated Hospital of Xinxiang Medical University from January 2020 to June 2020 were enrolled for a 24-month follow-up.Patients were divided into high erythropoietin resistance index(ERI)and low ERI groups based on median ERI,then compared the difference in hospitalization rate between the two groups,and analyzed related factors affecting the hospitalization rate.Results The hospitalization rate was positively correlated with age,increased body weight,ERI,hypersensitive C-reactive protein,negatively correlated with serum albumin,serum phosphorus and predialysis diastolic blood pressure.The results of multivariate logistic regression analysis showed that age and ERI were independent influencing factors for hospitalization in MHD patients.The results of Kaplan-Meier survival analysis showed that the hospitalization rate of the high ERI group was significantly higher than the low ERI group(P<0.001).Conclusion ERI and age are independent risk factors for increased hospitalization rates among MHD patients,and MHD patients with high ERI and advanced age are more likely to be hospitalized for various complications.

关 键 词：血液透析 促红细胞生成素 抵抗指数 住院患者 

分 类 号：R459.5[医药卫生—治疗学]