10%氯化钠腔内注射治疗部分性脾动脉栓塞术后脾脓肿的临床效果  

Clinical effect of intraventricular injection of 10%sodium chloride on splenic abscess after partial splenic embolization

作　　者：陈静 曹莉明 张勇学 崔进国 谢永伟 赵红恩 王敏 CHEN Jing;CAO Liming;ZHANG Yongxue;CUI Jinguo;XIE Yongwei;ZHAO Hongen;WANG Min(Department of Interventional Therapy,The 980th Hospital of PLA Joint Logistics Support Forces,Shijiazhuang 050082,China)

机构地区：[1]中国人民解放军联勤保障部队第九八〇医院(白求恩国际和平医院)介入治疗科,河北石家庄050082

出　　处：《医学影像学杂志》2023年第10期1836-1839,共4页Journal of Medical Imaging

基　　金：河北省卫生健康委员会医学科学研究青年课题项目(编号:20211761)。

摘　　要：目的探讨应用10%氯化钠注射液腔内注射治疗部分性脾动脉栓塞术(partial splenic arterial embolization,PSE)后脾脓肿的安全性及有效性。方法选取我院应用10%氯化钠注射液腔内注射治疗PSE术后脾脓肿6例患者的临床资料,CT引导下应用PTC针或注射器行脓肿穿刺抽取脓液后腔内注射10%氯化钠注射液,观察其临床疗效、血常规、肝功能变化及并发症情况。结果6例患者均取得满意疗效,穿刺次数1~2次,平均1.2次,所有患者术后1周发热、腹痛症状均明显缓解,术后2周症状消失。术后1周白细胞、中性粒细胞、血红蛋白及白蛋白水平较术前明显改善,术后1个月均恢复正常,差异有统计学意义(P<0.05)。随访6个月,6例临床症状均消失,5例痊愈,1例有效,所有患者均无复发,治疗期间无腹腔出血、腹膜炎及死亡等严重并发症发生。结论应用10%氯化钠溶液腔内注射治疗PSE术后脾脓肿疗效显著,不良反应少,可成为治疗脾脓肿的临床方法之一。Objective To discuss the safety and effectiveness of 10%sodium chloride injection in the treatment of splenic abscess after partial splenic artery embolization.Methods The clinical data of 6 cases of splenic abscess formed after partial splenic arterial embolization PSE treated by 10%sodium chloride injection in our hospital from January 2013 to February 2022 were retrospectively analyzed.PTC needle or syringe was used to perform abscess puncture and extract pus under the guidance of CT,and then 10%sodium chloride injection was injected intravenously.The clinical efficacy,blood routine,liver function changes and complications were observed.Results All the 6 patients achieved satisfactory curative effect,with 1~3 times of puncture(1.4 times on average).The levels of leukocytes,neutrophils,hemoglobin and albumin were significantly improved one week after surgery,and returned to normal one month after surgery,with statistical significance(P<0.05).Symptoms of fever and abdominal pain were significantly relieved in all patients one week after surgery,and disappeared two weeks after surgery.After 6 months of follow-up,5 cases were cured,1 case was effective,and no recurrence occurred.There were no serious complications such as abdominal bleeding,peritonitis and death occurred in all cases during treatment.Conclusion The intracapsular injection of 10%sodium chloride solution in the treatment of PSE postoperative spleen abscess has significant effect and less adverse reactions,which can be used as a treatment of spleen abscess.

关 键 词：脾脓肿 部分脾动脉栓塞术 氯化钠 介入性 放射学 

分 类 号：R657.6[医药卫生—外科学] R815[医药卫生—临床医学]