多感官刺激对脑卒中昏迷患者促醒效果的Meta分析  

Meta-analysis of the effect of multi-sensory stimulation on awakening in comatose patients after stroke

作　　者：郭怡航 苗润娜 吴红娟[2] 韩继明[1] 刘小玲[2] GUO Yihang;MIAO Runna;WU Hongjuan;HAN Jiming;LIU Xiaoling(Yan'an University,Xi'an,710068,China)

机构地区：[1]延安大学医学院,陕西省西安市710068 [2]陕西省人民医院,陕西省西安市710068

出　　处：《护理实践与研究》2023年第20期3027-3035,共9页Nursing Practice and Research

基　　金：陕西省自然科学基金面上项目(编号:2022JM-483)。

摘　　要：目的评价多感官刺激对脑卒中昏迷患者促醒的干预效果。方法计算机检索从建库至2023年1月10日PubMed、Web of Science、Embase、Cochrane Library、EBSCO、万方、中国知网、中国生物医学文献数据库、维普中英文期刊数据库中关于多感官刺激对脑卒中昏迷患者促醒效果的随机对照研究(RCTs)。采用Cochrane协作网中RCT的偏倚风险评价标准进行方法学质量评估,使用RevMan5.4统计软件进行Meta分析。结果最终纳入14篇RCTs文献,总样本量为853例。Meta分析结果显示,多感官刺激对脑卒中昏迷患者的格拉斯哥昏迷量表评分(MD=2.55,95%CI:2.22~2.88)、临床疗效(RR=1.88,95%CI:1.46~2.41)、清醒率(RR=1.91,95%CI:1.50~2.42)和清醒时间(SMD=-3.56,95%CI:-4.24~-2.88)均较对照组有所提高,差异均有统计学意义(P<0.05)。结论多感官刺激能够促进脑卒中昏迷患者苏醒,改善患者意识障碍。Objective To evaluate the intervention effect of multi-sensory stimulation on awakening in comatose patients after stroke.Methods We used computers to search for randomized controlled trials(RCTs)on the effect of multisensory stimulation on awakening in patients with stroke coma in PubMed,Web of Science,Embase,Cochrane Library,EBSCO,Wanfang,China National Knowledge Infrastructure,China Biomedical Literature Service Database,and VIP Chinese and English journal databases from inception to January 10,2023,and used the Cochrane Collaboration's risk of bias evaluation criteria for RCT to conduct methodological quality assessment,and used RevMan 5.4 statistical software to conduct Meta-analysis.Results A total of 14 RCTs were finally included,with a total sample size of 853 cases.The Meta-analysis results showed that the Glasgow coma scale(GCS)score(MD=2.55,95%CI:2.22~2.88),clinical efficacy(RR=1.88,95%CI:1.46~2.41),wakefulness rate(RR=1.91,95%CI:1.50~2.42),and wakefulness time(SMD=-3.56,95%CI:-4.24~-2.88)of multisensory stimulation patients in stroke coma were all improved compared with the control group,and the differences were statistically significant(P<0.05).Conclusion Multisensory stimulation can promote the awakening of comatose patients after stroke and improve their consciousness disorder.

关 键 词：多感官刺激 脑卒中 昏迷 促醒 META分析 

分 类 号：R473.5[医药卫生—护理学]