席汉综合征并发急性胰腺炎诊治分析及文献复习  

Sheehan's Syndrome Complicated by Acute Pancreatitis:A Case Report and Literature Review

作　　者：李嘉慧 孙昀[2] 鹿中华[2] 曹利军[2] 王炳然 张浩楠 Li Jia-hui;SUN Jun;Lu Zhong-hua;Cao Li-jun;Wang Bing-ran;Zhang Hao-nan(Anhui Medical University,Hefei 230601,Anhui Province,China;Department of Critical Care Medicine,the Second Affiliated Hospital of Anhui Medical University,Hefei 230601,Anhui Province,China)

机构地区：[1]安徽医科大学,安徽合肥230601 [2]安徽医科大学第二附属医院重症医学科,安徽合肥230601

出　　处：《罕少疾病杂志》2023年第10期1-3,共3页Journal of Rare and Uncommon Diseases

基　　金：安徽医科大学第二附属医院临床研究培育计划项目(2020LCZD08);2021年度安徽省高等学校省级质量工程项目(2021jyxm0703)。

摘　　要：目的总结席汉综合征合并急性胰腺炎的临床特征及诊治经过,以期获得临床重视。方法回顾性分析1例席汉综合征合并急性胰腺炎患者的临床资料,并复习相关文献。结果经CNKI、PubMed数据库检索相关病例7例,结合本院收治1例得到以下结果。8例患者病程中均接受激素替代治疗;并发胰腺炎时,甲状腺激素水平均显著下降;3名患者患有高脂血症,有2名被明确诊断为高甘油三酯血症性胰腺炎;6例患者并发急性胰腺炎无明显诱因,考虑其发病与席汉综合征导致垂体功能低下从而引起激素合成障碍相关。结论席汉综合征所表现的垂体功能减退可并发急性胰腺炎。对席汉综合征患者应定期复查激素水平、调整替代药物的剂量;患者出现腹痛等症状时需及时行相关检查排除急性胰腺炎;一旦诊断胰腺炎,应及时采取针对性治疗。Objective To summarize the clinical features,diagnosis and treatment of Sheehan syndrome complicated with acute pancreatitis.Methods Retrospectively analyze a case of Sheehan syndrome complicated with acute pancreatitis and review the relevant literature.Results Through CNKI and PubMed databases,a total of 7 related cases were retrieved,and the following results were obtained by combining 1 case admitted to our hospital.All patients received hormone replacement therapy during the course of disease;When complicated with pancreatitis,thyroid hormone levels decreased significantly;Three patients had hyperlipidemia and two had a definite diagnosis of hypertriglyceridemia pancreatitis;6 patients with acute pancreatitis had no obvious cause,which was considered to be related to hormone synthesis disorder caused by hypopituitarism caused by Sheehan syndrome.Conclusions Hypopituitarism in Sheehan syndrome can be complicated by acute pancreatitis.For patients with Sheehan syndrome,hormone levels should be reexamined regularly and the dosage of alternative drugs should be adjusted;Patients with abdominal pain and other symptoms should be timely examined to rule out acute pancreatitis;Once pancreatitis is diagnosed,targeted treatment should be taken in time.

关 键 词：席汉综合征 急性胰腺炎 垂体功能低下 

分 类 号：R657.51[医药卫生—外科学]