颈动脉狭窄患者支架置入术后发生认知功能障碍的相关危险因素分析  

Risk Factors of Cognitive Dysfunction in Patients with Carotid Artery Stenosis after Stent Implantation

作　　者：熊杨 朱剑[1] 张丽[1] Xiong Yang;Zhu Jian;Zhang Li(The Second Affiliated Hospital of Nanchang University,Nanchang 330000,Jiangxi Province,China)

机构地区：[1]南昌大学第二附属医院,江西南昌330000

出　　处：《罕少疾病杂志》2023年第10期6-7,共2页Journal of Rare and Uncommon Diseases

摘　　要：目的分析颈动脉狭窄(CS)患者支架置入术后发生认知功能障碍(POCD)的相关危险因素。方法选取医院2020年1月-2023年1月接受支架置入术治疗的117例CS患者,采用蒙特利尔认知评估量表(MoCA)评估患者支架置入术后POCD发生情况,调查患者一般资料,纳入可能的因素,重点分析CS患者支架置入术后发生POCD的相关危险因素。结果117例CS患者支架置入术后发生POCD 19例,发生率为16.24%;经Logistics回归分析显示,年龄≥60岁、合并高血压、动脉粥样硬化史、吸烟史、颈动脉重度狭窄、焦虑抑郁是CS患者支架置入术后发生POCD的危险因素(OR>1,P<0.05)。结论CS患者支架置入术后发生POCD高风险,受年龄、合并高血压、动脉粥样硬化史、吸烟史、颈动脉狭窄程度、焦虑抑郁因素影响。Objective To analyze the risk factors of cognitive dysfunction(POCD)after stent implantation in patients with carotid artery stenosis(CS).Methods A total of 117 patients with CS who received stent implantation from January 2020 to January 2023 were selected from the hospital.The occurrence of POCD after stent implantation was assessed using the Montreal Cognitive Assessment Scale(MoCA).General information of the patients was investigated and possible factors were included.The risk factors of POCD in CS patients after stent implantation were analyzed.Results POCD occurred in 19 of 117 CS patients(16.24%)after stent implantation.Logistics regression analysis showed that age≥60 years old,combined with hypertension,atherosclerosis history,smoking history,severe carotid artery stenosis,anxiety and depression were risk factors for POCD in CS patients after stent implantation(OR>1,P<0.05).Conclusion CS patients are at high risk of developing POCD after stent implantation,which is affected by age,hypertension,history of atherosclerosis,smoking history,degree of carotid artery stenosis,anxiety and depression.

关 键 词：颈动脉狭窄 支架置入术 认知功能障碍 危险因素 

分 类 号：R248.2[医药卫生—中医临床基础]