HR-MRI分析MCAS患者管壁特征和斑块与卒中风险的关系  

Analysis of Vascular Wall Characteristics and the Relationship Between Plaques and Stroke Risk in MCAS Patients by HR-MRI

作　　者：戴迎桂 张娴娴 董从松 刘洋[1] 柏荣荣 DAI Ying-gui;ZHANG Xian-xian;DONG Cong-song;LIU Yang;BAI Rong-rong(Imaging Department,Nanjing Medical University Yancheng Clinical Medical College,Yancheng Third People's Hospital,Yancheng 224008,Jiangsu Province,China;Neurology Department,Nanjing Medical University Yancheng Clinical Medical College,Yancheng Third People's Hospital,Yancheng 224008,Jiangsu Province,China)

机构地区：[1]南京医科大学盐城临床医学院、盐城市第三人民医院影科,江苏盐城224008 [2]南京医科大学盐城临床医学院、盐城市第三人民医院神经内科,江苏盐城224008

出　　处：《中国CT和MRI杂志》2023年第10期53-55,共3页Chinese Journal of CT and MRI

基　　金：盐城市医学科技发展计划项目(YK2020070)。

摘　　要：目的利用高分辨率磁共振(HR-MRI)分析大脑中动脉狭窄(MCAS)患者管壁特征和斑块与卒中风险的关系。方法选取2020年10月至2022年10月在本院收治的MCAS患者78例,根据其是否发生急性卒中分为急性卒中组(n=36)和非急性卒中组(n=42),均完善HR-MRI检查,比较两组患者MCA狭窄处血管壁及斑块特征,利用多因素Logistic回归分析影响M CAS患者的独立危险因素,ROC曲线评价指标预测MCAS患者卒中的价值。结果急性卒中组LA值低于非急性卒中组,NWI、PA值高于非急性卒中组,斑块强化程度高于非急性卒中组,正性重构率高于非急性卒中组(P<0.05);多因素Logistic回归分析显示LA、PA值和斑块强化程度为影响MCAS患者发生急性卒中的独立危险因素(P<0.05)。ROC曲线分析结果示LA、PA值和斑块强化程度均具有预测MCAS患者急性卒中的价值(P<0.05)。结论HRM RI可对M CAS患者管壁特征和斑块特征进行评估,LA、PA值和斑块强化程度是影响MCAS患者发生卒中的独立危险因素,且具有预测价值。Objective To analyze vascular wall characteristics and the relationship between plaques and stroke risk in patients with middle cerebral artery stenosis(MCAS)by high-resolution magnetic resonance imaging(HR-MRI).Methods A total of 78 patients with MCAS admitted to the hospital were enrolled between October 2020 and October 2022.According to presence or absence of acute stroke,they were divided into acute stroke group(n=36)and nonacute stroke group(n=42).All underwent HR-MRI examination.The characteristics of vascular walls and plaques at MCAS sites were compared between the two groups.The independent risk factors in MCAS patients were analyzed by multivariate Logistic regression analysis.The predictive value of different indexes for stroke of MCAS patients was evaluated by ROC curves.Results LA in acute stroke group was lower than that in non-acute stroke group,NWI and PA were higher than those in non-acute stroke group,plaque enhancement degree was higher than that in non-acute stroke group,and positive remodeling rate was higher than that in non-acute stroke group(P<0.05).Multivariate Logistic regression analysis showed that LA,PA and plaque enhancement degree were independent risk factors of acute stroke in MCAS patients(P<0.05).The results of ROC curves analysis showed that LA,PA and plaque enhancement degree were of predictive value for acute stroke in MCAS patients(P<0.05).Conclusion HR-MRI can be applied to evaluate the characteristics of vascular walls and plaques in MCAS patients.LA,PA and plaque enhancement degree are independent risk factors of stroke,which all have predictive value.

关 键 词：高分辨率磁共振 大脑中动脉狭窄 管壁特征 斑块特征 卒中风险 

分 类 号：R445.2[医药卫生—影像医学与核医学]