肥胖导致的缺铁及其对妊娠结局的影响  

Obesity-related iron deficiency and its impact on pregnancy outcomes

作　　者：王欣颖 魏玉梅[1] Wang Xinying;Wei Yumei(Department of Obstetrics and Gynecology,Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学第一医院妇产科,北京100034

出　　处：《中华围产医学杂志》2023年第9期778-781,共4页Chinese Journal of Perinatal Medicine

基　　金：国家重点研发计划(2021YFC2700705)。

摘　　要：肥胖和缺铁都是妊娠期最常见的合并症。缺铁可导致缺铁性贫血,并影响子代生长发育,尤其是神经系统的发育。肥胖可导致孕妇机体处于炎症状态并使铁调素的表达升高,从而使孕妇缺铁。但目前肥胖导致的缺铁是否会导致不良妊娠结局暂无定论。故本综述重点阐述肥胖导致的缺铁,及其对妊娠结局的影响的研究进展。Obesity and iron deficiency are the most common pregnancy complications.Iron deficiency can lead to anemia and affects the growth and development of offspring,especially the nervous system.Maternal obesity induces mild inflammation and can up-regulate the expression of hepcidin,which leads to maternal iron deficiency.At present,the correlation between obesity-related iron deficiency and adverse pregnancy outcomes is controversial.Therefore,this review focuses on the research progress in obesity-related iron deficiency and its effect on pregnancy outcomes.

关 键 词：妊娠期肥胖 铁缺乏症 胎儿发育 妊娠结局 

分 类 号：R714.256[医药卫生—妇产科学]