基于酸甘化阴理论探讨药食同源品种山茱萸-炙甘草药对的心肌保护作用  

Discussion on the Protective Effect on the Myocardium of Medicinal and Edible Herb Couple of Corni Fructus-Glycyrrhizae Radix et Rhizoma Praeparata cum Melle Based on the Theory of Nourishing Yin with Sour and Sweet Tastes

作　　者：冀迅 梁慧 时洋凯 张瑜[1] 任梦娇 余黎[2] 魏凯峰[1] 刘涛[1] JI Xun;LIANG Hui;SHI Yang-kai;ZHANG Yu;REN Meng-jiao;YU Li;WEI Kai-feng;LIU Tao(School of Chinese Medicine,School of Integrated Chinese and Western Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China;School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210023,China)

机构地区：[1]南京中医药大学中医学院·中西医结合学院,江苏南京210023 [2]南京中医药大学药学院,江苏南京210023

出　　处：《南京中医药大学学报》2023年第9期954-960,共7页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：国家中医药管理局高水平中医药重点学科建设项目资助(国中医药人教函〔2023〕85号);杨进全国名老中医药专家传承工作室;杨进江苏省名老中医药专家传承工作室。

摘　　要：各种心肌损伤因素造成的相关疾病往往预后不佳,且用药疗程较长,是临床亟待解决的重要问题。研究发现,酸甘化阴治法对慢性心肌病有显著疗效,通过文献研究和实验筛选,发现药食同源品种山茱萸-炙甘草药对可改善心肌损伤。故从酸甘化阴理论角度,对山茱萸-炙甘草保护心肌、缓解心肌损伤的作用进行探讨,以期更好地指导山茱萸-炙甘草在临床中的使用以及为药食同源品种的研究开发与应用提供参考。Because of the high safety of medicinal and edible herbs,they are increasingly used in the prevention and treatment of diseases,especially chronic diseases.Myocardial related diseases caused by various myocardial injuries often have poor prognosis,which is an important problem needed to be solved urgently in clinic.Based on a large number of clinical practice experience of Professor WEI Kai-feng and modern pharmacological research,it is found that treatment of Nourishing Yin with Sour and Sweet Tastes has obvious curative effect on chronic cardiomyopathy.In order to facilitate long-term drug use,we conducted literature and experimental research on the varieties of medication-food homologous Chinese medicinal materials under the guidance of the theory of Nourishing Yin with Sour and Sweet Tastes,and finally focused on the improvement of myocardial injury by Corni Fructus-Glycyrrhizae Radix et Rhizoma Praeparata cum Melle drug pair.This article will discuss the theory of Nourishing Yin with Sour and Sweet Tastes,and the research status of Corni Fructus-Glycyrrhizae Radix et Rhizoma Praeparata cum Melle drug pair in alleviating myocardial injury under the guidance of this theory,in order to promote the application of varieties with the medicinal and edible herbs,and better serve for clinical problem solving.

关 键 词：酸甘化阴 山茱萸 炙甘草 心肌损伤 

分 类 号：R285.6[医药卫生—中药学]