腕管综合征发病危险因素的病例对照研究  

A case-control study on risk factors for carpal tunnel syndrome

作　　者：陈曦 曹瑾瑾[1,2,3,4,5] 芮晶 劳杰 Chen Xi;Cao Jinjin;Rui Jing;Lao Jie(Department of Hand Surgery,Huashan Hospital,Fudan University,Shanghai 200040,China;NHC Key Laboratory of Hand Reconstruction(Fudan University),Shanghai 200032,China;Shanghai Key Laboratory of Peripheral Nerve and Microsurgery,Shanghai 200032,China;Institute of Hand Surgery,Shanghai 200040,China;Institute of Hand Surgery,Fudan University,Shanghai 200040,China)

机构地区：[1]复旦大学附属华山医院手外科,上海200040 [2]卫健委手功能重建重点实验室,上海200032 [3]上海市周围神经显微外科重点实验室,上海200032 [4]上海市手外科研究所,上海200040 [5]复旦大学手外科研究所,上海200040

出　　处：《中华手外科杂志》2023年第4期331-335,共5页Chinese Journal of Hand Surgery

基　　金：国家自然科学基金面上项目(81972122,81971150);上海市临床重点专科项目(shslczdzk05601);上海市周围神经显微外科重点实验室(20DZ2270200)。

摘　　要：目的研究影响腕管综合征(CTS)发病的危险因素,为高危人群的疾病预防提供依据。方法选取我科自2019年12月至2021年1月收治的CTS患者236例为疾病组,年龄区间和性别比例相同的非CTS患者96例为对照组,进行问卷调查、体格检查和神经电生理检查并记录各项临床数据。各因素对腕管综合征的发病率影响作Logistic回归分析。结果优势手的比值比(OR)为1.113,差异无统计学意义(P>0.05);年龄OR为1.023,差异无统计学意义(P>0.05);吸烟OR为2.284,差异有统计学意义(P<0.05);饮酒OR为0.598,差异无统计学意义(P>0.05);重体力劳动OR为3.436,差异有统计学意义(P<0.05);厨师OR为4.523,差异有统计学意义(P<0.05);糖尿病OR为3.714,类风湿性关节炎OR为12.108,差异有统计学意义(P<0.05);甲状腺功能减退OR为3.869,甲状腺功能亢进OR为0.824,高血压OR为0.811,差异无统计学意义(P>0.05)。结论吸烟、重体力劳动、厨师、糖尿病、类风湿性关节炎可能是腕管综合征发病的高危因素。对有危险因素的人群进行针对性预防,将有希望降低CTS的发病率。Objective To study the risk factors that affect the onset of carpal tunnel syndrome(CTS)and provide a basis for disease prevention in high-risk populations.Methods A total of 236 patients with CTS admitted from December 2019 to January 2021 in our department were selected as the disease group,and 96 patients without CTS the same age range and sex ratio were selected as the control group.Questionnaire survey,physical examination and neuro-electrophysiological examination were conducted and various clinical data were recorded.Logistic regression analysis was made on the influence of various factors on the incidence rate of CTS.Results The odds ratio(OR)of the dominant hand was 1.113,and the difference was not statistically significant(P>0.05).The OR for age was 1.023,with no statistically significant difference(P>0.05).The OR for smoking was 2.284,with a statistically significant difference(P<0.05).The OR for alcohol consumption was 0.598,with no statistically significant difference(P>0.05).The OR for heavy physical labor was 3.436,with a statistically significant difference(P<0.05).The OR of the chef was 4.523,with a statistically significant difference(P<0.05).The OR for diabetes was 3.714,for rheumatoid arthritis was 12.108,and the difference was statistically significant(P<0.05).The OR for hypothyroidism was 3.869,for hyperthyroidism was 0.824,and for hypertension was 0.811,with no statistically significant difference(P>0.05).Conclusion The smoking,heavy physical labor,cooks,diabetes and rheumatoid arthritis may be high risk factors for CTS.The targeted prevention for people with risk factors will hopefully reduce the incidence rate of CTS.

关 键 词：腕管综合征 危险因素 病因学 发病率 

分 类 号：R688[医药卫生—骨科学]