628例食源性腹泻患者沙门菌血清型分布及药敏分析  

Serotype Distribution and Drug Susceptibility Analysis of Salmonella in 628 Patients with Food-Borne Diarrhea

在线阅读下载全文

作  者:肖青 方根成 薛喜梅 钱留军 XIAO Qing;FANG Cheng-gen;XUE Xi-mei;QIAN Liu-jun(Microbiological Examination,Queshan County Center for Disease Control and Prevention,Zhumadian 463299,China;Queshan People's Hospital,Zhumadian 463299,China)

机构地区:[1]确山县疾病预防控制中心微生物检验,驻马店463299 [2]确山县人民医院,驻马店463299

出  处:《四川解剖学杂志》2023年第3期92-94,共3页Sichuan Journal of Anatomy

摘  要:目的:探讨628例食源性腹泻患者沙门菌血清型分布及药敏情况.方法:收集2021年2月至2023年3月于确山县辖区各医院门诊就诊的628例食源性腹泻患者的检出沙门菌,实施细菌分离鉴定、药物敏感试验,分析沙门菌血清型分布情况及药敏情况.结果:628株沙门菌中以鼠伤寒沙门菌单相变种最为常见,占34.08%,其次为鼠伤寒沙门菌、肠炎沙门菌,分别占21.02%、18.31%.628株沙门菌对氨苄西林、氯霉素、四环素、复方新诺明、复方新诺明耐药率较高,均超过60%,未检出对亚胺培南耐药菌株,且对头孢西丁耐药率较低.沙门菌耐药菌株占93.95%(590/628),多重耐药菌占85.51%(537/628),耐受≥10种抗生素菌株占12.58%(79/628).结论:食源性腹泻患者沙门菌血清型多见于鼠伤寒沙门菌单相变种、鼠伤寒沙门菌、肠炎沙门菌,沙门菌耐药情况严重,临床需加大沙门菌耐药监测,根据药敏结果合理选择抗菌药物,以期提高治疗效果、改善患者预后.Objective:To investigate the serotype distribution and drug susceptibility of salmonella in 628 patients with food-borne diarrhea.Methods:Salmonella strains isolated from 628 patients with foodborne diarrhea who visited the outpatient department of each hospital in Queshan County from February 2021 to March 2023 were collected,and bacterial isolation,identification and drug susceptibility tests were carried out to analyze the distribution of salmonella serotypes and drug susceptibility.Results:Among 628 strains of Salmonella typhimurium,monophasic strain was the most common,accounting for 34.08%,followed by Salmonella typhimurium and Salmonella enteritidis,accounting for 21.02%and 18.31%,respectively.The resistance rate of 628 salmonella strains to ampicillin,chloramphenicol,tetracycline,cotrimoxazole and cotrimoxazole was higher than 60%,no imipenem resistant strains were detected,and the resistance rate to cefoxitin was low.Drug-resistant bacteria accounted for 93.95%(590/628),multi-drug-resistant bacteria accounted for 85.51%(537/628),and strains resistant to≥10 antibiotics accounted for 12.58%(79/628).Conclusion:Salmonella serotypes in food-borne diarrhea patients are more common in monophase variant of Salmonella typhimurium,Salmonella typhimurium,and Salmonella enteritidis.The drug resistance of salmonella is serious.Clinical monitoring of salmonella resistance should be strengthened,and antibiotics should be reasonably selected according to the drug sensitivity results,in order to improve the therapeutic effect and prognosis of patients.

关 键 词:食源性腹泻 沙门菌 血清型 药敏反应 

分 类 号:R446.5[医药卫生—诊断学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象