刘磊运用抑酸合剂加减治疗食管癌术后胃食管反流经验撷菁  

Summary of LIU Lei’s Experience in Treating Gastroesophageal Reflux after Surgery for Esophageal Cancer using Modified Acid-suppressing Mixtures

作　　者：王寒笑 刘磊[2] WANG Hanxiao;LIU Lei(Taihe County Hospital of Traditional Chinese Medicine Affiliated of Anhui University of Chinese Medicine,Anhui Fuyang 236600,China;Taihe Hospital of Traditional Chinese Medicine,Anhui Fuyang 236600,China)

机构地区：[1]安徽中医药大学附属太和中医院,安徽阜阳236600 [2]安徽省阜阳市太和县中医院,安徽阜阳236600

出　　处：《中医药临床杂志》2023年第10期1948-1953,共6页Clinical Journal of Traditional Chinese Medicine

基　　金：安徽省中医药传承创新科研项目(2020ccyb21)。

摘　　要：食管癌(esophageal cancer,EC)是中国常见的消化道恶性肿瘤之一,其病死率约占世界食管癌病死率的1/3。食管癌早期临床症状不明显,大多数患者常因胸骨后疼痛、进食梗阻就医,此时多处于疾病的中晚期。目前临床对此病的治疗主以手术切除为主,此法虽能有效清除癌变组织,提高患者生存率,但术中食管及胃解剖位置的改变,常会引起术后胃食管反流症状的发生,严重影响患者的生活质量。现代医学虽能暂缓此病,解决反酸问题,但其长期使用易产生耐药性,停药后易复发。刘磊,安徽中医药大学副教授,硕士研究生导师,皖北名医,主任医师,全国中医药创新骨干人才,长期从事胸外科疾病基础与临床工作研究。刘磊副教授认为,食管癌术后胃食管反流病位在脾胃,病机为脾胃虚弱,升降失调,肝气郁滞,日久化火生酸,治疗上以健胃醒脾、开郁降气为主。结合团队前期理论研究及多年临床经验,刘磊副教授认为,中医学在治疗食管癌术后胃食管反流方面疗效较好,术后使用经验方—抑酸合剂,可有效促进患者胃肠动力恢复,改善胃食管反流症状,进而提高患者生活质量。附临床验案1例予以佐证。Esophageal cancer(EC)is one of the common malignant tumors of the digestive tract in China,and its mortality rate accounts for approximately 1/3 of the esophageal cancer mortality rate in the world.The early clinical symptoms of esophageal cancer are not obvious.Most patients often seek medical treatment for retrosternal pain and obstruction of eating.At this time,most patients are in the middle and late stages of the disease.The current clinical treatment for this disease is mainly surgical resection.Although this method can effectively remove cancerous tissue and improve the survival rate of patients,the changes in the anatomical position of the esophagus and stomach during surgery often lead to postoperative gastroesophageal reflux symptoms,seriously affecting the patient’s quality of life.Although modern medicine can delay the disease and solve the problem of acid reflux,long-term use can easily lead to drug resistance and relapse after drug withdrawal.LIU Lei,associate professor at Anhui University of Traditional Chinese Medicine,master’s tutor,famous doctor in northern Anhui,chief physician,national innovative backbone of traditional Chinese medicine,has long been engaged in basic and clinical research on thoracic surgical diseases.Associate Professor LIU Lei believes that the location of gastroesophageal reflux after esophageal cancer surgery is in the spleen and stomach.The pathogenesis is weakness of the spleen and stomach,imbalance of ascending and descending,stagnation of liver qi,which turns into fire and produces acid over time.The treatment is mainly to strengthen the stomach,awaken the spleen,and relieve stagnation and lower Qi.Combining the team’s preliminary theoretical research and years of clinical experience,Associate Professor LIU Lei believes that traditional Chinese medicine is effective in treating gastroesophageal reflux after surgery for esophageal cancer.The use of empirical prescriptions after surgery-acid-suppressing mixture can effectively promote the recovery of gastrointestin

关 键 词：食管癌术后 抑酸合剂加减 胃食管反流 刘磊 名医经验 

分 类 号：R269[医药卫生—中西医结合]