广西壮族自治区2005-2021年新报告男男性行为人群HIV感染者晚发现及影响因素分析  

Analysis of late-diagnosis and associated factors in newly reported HIV infections among men who have sex with men in Guangxi Zhuang Autonomous Region, 2005-2021

作　　者：侯文宣 江河[2] 朱秋映[2] 黄精华[2] 李剑军[2] 吴秀玲[2] 刘玄华[2] 梁能秀[2] 唐帅[2] 孟琴[2] 李博 陈妮 蓝光华 Hou Wenxuan;Jiang He;Zhu Qiuying;Huang Jinghua;Li Jianjun;Wu Xiuling;Liu Xuanhua;Liang Nengxiu;Tang Shuai;Meng Qin;Li Bo;Chen Ni;Lan Guanghua(Guangxi University of Chinese Medicine,Nanning 530028,China;Guangxi Key Laboratory of AIDS Prevention and Control and Achievement Transformation/Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention,Nanning 530028,China;Youjiang Medical University for Nationalities,Baise 533000,China)

机构地区：[1]广西中医药大学,南宁530028 [2]广西壮族自治区疾病预防控制中心/广西艾滋病防控与成果转化研究重点实验室,南宁530028 [3]右江民族医学院,百色533000

出　　处：《中华流行病学杂志》2023年第10期1646-1652,共7页Chinese Journal of Epidemiology

基　　金：国家自然科学基金(82160636)。

摘　　要：目的分析广西壮族自治区(广西)防治艾滋病攻坚工程开展前后MSM HIV感染者(MSM感染者)的晚发现变化趋势及其影响因素,从中寻找现阶段需要优先干预的人群。方法从中国疾病预防控制信息系统艾滋病防治基本信息系统中选取2005-2021年广西新报告的MSM感染者作为研究对象。采用Joinpoint 4.9.1.0软件对晚发现病例和非晚发现病例进行时间趋势检验,运用logistic回归分析各阶段晚发现的影响因素。结果2005-2021年广西新报告MSM感染者共5764例,晚发现比例为28.45%(1640例)。以2015年为界,晚发现比例呈先急速下降后趋于稳定的趋势,平均年度变化百分比=-6.90%(P<0.001),2010年后常住人口、职业为农民工和样本来源于就诊医疗等因素在攻坚工程开展前后对晚发现的影响效应变化较大,现阶段晚发现的影响因素有年龄、常住人口、职业为农民工和学生。结论攻坚工程前后广西新报告MSM感染者的晚发现比例下降趋势明显,但晚发现仍不容忽视,需针对常住人口、农民工和学生人群开展精准防控。Objective To analyze the trend of late-diagnosis of HIV-infected men who have sex with men(MSM)before and after the AIDS Conquering Project in Guangxi Zhuang Autonomous Region(Guangxi)and its influencing factors,in order to find out the population groups that need priority intervention at the present stage.Methods The HIV-infected MSM in Guangxi from 2005-2021 were selected from the National Integrated HIV/AIDS Control and Prevention Data System.The Joinpoint 4.9.1.0 software was used to test the time trend of late-diagnosis and non-late-diagnosis cases,and logistic regression was applied to analyze the factors influencing the proportion of late-diagnosis at each stage.Results From 2005 to 2021,5764 HIV-infected MSM were reported in Guangxi from 2005 to 2021,with an overall late-diagnosis of 28.45%(1640 cases).Under the 2015 baseline data as the boundary,the proportion of late-diagnosis cases showed a trend of sharp decline followed by stabilization from 2005 to 2015,average annual percent change=-6.90%(P<0.001).The effect of factors such as resident population,occupation as a farmer or worker,and sample originating from medical consultation on late-diagnosis changed considerably before and after the implementation of the project,and the factors influencing late-diagnosis at this stage were age,resident population,occupation as a farmer,worker or student.The factors influencing late-diagnosis at this stage are age,resident population,and occupation as a farmer,worker and a student.Conclusions The proportion of late diagnosis cases of HIV-infected MSM in Guangxi decreased significantly before and after the project.However,late-diagnosis should not be neglected and precise prevention and control should be carried out for the resident population,farmers,workers or students.

关 键 词：艾滋病 晚发现 男男性行为人群 影响因素 

分 类 号：R512.91[医药卫生—内科学] R181.3[医药卫生—临床医学]