基于数据挖掘的针灸治疗肿瘤相关性抑郁选穴规律研究  

Acupoints Selection Rule of Acupuncture and Moxibustion in Treatment of CRD Based on Data Mining

作　　者：赵锦涛 王亚军[1] 赵霞[2] 王文超 姜升 ZHAO Jintao;WANG Yajun;ZHAO Xia;WANG Wenchao;JIANG Sheng(Gansu University of Chinese Medicine,Lanzhou 730030,China;Gansu Provincial Hospital of TCM,Lanzhou 730050,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730030 [2]甘肃省中医院,甘肃兰州730050

出　　处：《针灸临床杂志》2023年第10期81-87,共7页Journal of Clinical Acupuncture and Moxibustion

基　　金：国家自然科学基金地区科学基金,编号:82160936。

摘　　要：目的:运用数据挖掘技术探讨针灸治疗肿瘤相关性抑郁(CRD)的选穴规律。方法:通过检索中国期刊全文数据库(CNKI)、万方数据知识服务平台(Wanfang)、维普中文科技期刊数据库(VIP)、PubMed和中国生物医学文献服务系统(SinoMed)建库至2022年9月30日针灸治疗CRD的临床研究文献。采用Excel 2010软件建立选穴处方数据库,统计腧穴频次及频率使用情况,并采用SPSS Modeler 18.0软件对处方进行关联规则分析,SPSS 22.0软件进行聚类分析,Gephi0.9.1软件进行复杂网络分析。结果:共纳入71篇文献,包含83条针灸处方,涉及79个腧穴,腧穴使用总频次为582次。足三里、内关、三阴交、太冲与合谷为针灸治疗CRD使用频次前5位的腧穴,所用腧穴多分布于下肢部,腧穴归经以足太阳经频次最高,百会-印堂、合谷-足三里等为针灸治疗CRD的高频穴对。结论:临床针灸治疗CRD以脏腑辨证选穴为主,远近配穴和经脉配穴相结合,核心腧穴为足三里、内关、三阴交、太冲与合谷等,并根据临床辨证灵活加减腧穴组合以通督醒脑、解郁安神,达到治疗效果。Objective:To explore the acupoints selection rule of acupuncture and moxibustion in treating cancer-related depression(CRD)by using data mining techniques.Methods:The clinical research literature on acupuncture and moxibustion for CRD was retrieved by searching the databases of CNKI,Wanfang,VIP,PubMed and SinoMed from the establishments to September 30,2022.Excel 2010 software was used to establish the database of selected acupoint prescriptions,and the frequency use of acupoints was counted,SPSS Modeler 18.0 software was used for association rule analysis of prescriptions,SPSS 22.0 software for cluster analysis and Gephi 0.9.1 software for complex network analysis.Results:A total of 71 literature contained 83 acupuncture prescriptions involving 79 acupoints,and the total frequency of acupoints used was 582 times.Zusanli(ST36),Neiguan(PC6),Sanyinjiao(SP6),Taichong(LR3)and Hegu(LI4)were the top five acupoints used in treatment of CRD by acupuncture and moxibustion,and the acupoints used were mostly distributed in the lower extremities,with the highest frequency of acupoints attributed to foot-Taiyang meridian,and Baihui(DU20)-Yintang(EX-HN3)and LI4-ST36 were the high-frequency pairs for treating CRD.Conclusion:Clinical acupuncture treatment for CRD focuses on acupoints selection based on identification of internal organs,and the combination of distant points,local points and meridian points,with the core points of ST36,PC6,SP6,LR3 and LI4.The combination of acupoints is flexibly modified to activate Du meridian and clear mind,relieve depression and calm Shen based on syndrome differentiation to achieve therapeutic effects.

关 键 词：肿瘤 抑郁 郁证 针灸 选穴规律 数据挖掘 

分 类 号：R246.6[医药卫生—针灸推拿学]