超声造影与增强电子计算机断层扫描引导下经皮肺周围型肿物穿刺活检的应用价值比较  

Comparison study on application of contrast-enhance ultrasound and contrast-enhance computed tomography guided percutaneous biopsy of peripheral lung lesions

作　　者：梁凯迪 于晶 李玥 曹军英 张筠 Liang Kaidi;Yu Jing;Li Yue;Cao Junying;Zhang Yun(Department of Ultrasound Diagnosis,General Hospital of Northern Theater Command,Shenyang 110016,China)

机构地区：[1]北部战区总医院超声诊断科,沈阳110016

出　　处：《中国临床实用医学》2023年第4期35-38,共4页China Clinical Practical Medicine

基　　金：辽宁省科学技术计划项目(2020JH2/10300122);沈阳市科技计划项目(20-205-4-058)。

摘　　要：目的探讨超声造影与增强电子计算机断层扫描(CT)引导下经皮肺周围型肿物穿刺活检的应用价值。方法本研究为病例对照研究,选取2019年9月至2022年8月于北部战区总医院胸外科就诊的72例肺周围型肿物患者,男49例,女23例,年龄(63.56±10.98)岁,年龄范围为36~79岁。根据穿刺引导方式不同将患者分为超声造影组(n=30)与增强CT组(n=42)。比较两组患者的穿刺成功率、并发症发生率及病理结果,比较超声造影组良、恶性肿物内部增强特征。结果超声造影组穿刺成功率[93.3%(28/30)]与增强CT组穿刺成功率[88.1%(37/42)]比较,差异无统计学意义(P>0.05)。超声造影组穿刺并发症发生率[3.3%(1/30)]低于增强CT组[14.2%(9/42)],差异有统计学意义(P<0.05)。超声造影组中良性肿物超声造影到达时间[(8.36±1.81)s]早于恶性肿物超声造影到达时间[(13.91±2.98)s],差异有统计学意义(P<0.05)。超声造影组良、恶性肿物造影增强水平、造影剂分布、达峰时间及峰值强度比较,差异均无统计学意义(P>0.05)。结论超声造影引导下肺周围型肿物穿刺活检并发症低于增强CT组,超声造影剂到达时间对肺周围型肿物良恶性的诊断中具有一定的鉴别意义。Objective To explore the application of contrast-enhance ultrasound(CEUS)and contrast-enhance computed tomography(CT)guided percutaneous biopsy of peripheral lung lesions.Methods This study was a case-control study,a total of 72 patients with peripheral lung lesions treated in the Chest Surgery department of General Hospital of Northern Theater Command from September 2019 to August 2022,including 49 males and 23 females,aged(63.56±10.98)years old,age from 36 to 79 years old.Divide patients into CEUS group(n=30)and contrast-enhance CT group(n=42)based on different guidance methods.Compared the success rate,complication rate and postoperative pathology between two groups,compared the enhanced features of benign and malignant lesions in CEUS group.Results Compared the the success rate of biopsy in CEUS group was[93.3%(28/30)]with contrast-enhance CT group was[88.1%(37/42)],there was no statistically significant(P>0.05).The incidence of puncture complications in CEUS group was[3.3%(1/30)]lower than contrast-enhance CT group[14.2%(9/42)],the difference was statistically significant(P<0.05).In CEUS group the arrive time in the benign lesions[(8.36±1.81)s]sooner than that in the malignant lesions[(13.91±2.98)s],the difference was statistically significant(P<0.05).There were no statistically significant of the enhancement level,contrast agent distribution,time to peak and peak intensity between benign and malignant lesions in CEUS group(P>0.05).Conclusions The incidence of complications CEUS group in peripheral pulmonary lesions is lower than contrast-enhance CT group,the arrive time of CEUS has certain differential significance in the diagnosis of benign and malignant peripheral lung lesions.

关 键 词：超声造影 增强电子计算机断层扫描 肺周围型肿物 穿刺活检 病理 

分 类 号：R445.1[医药卫生—影像医学与核医学] R734.2[医药卫生—诊断学]