不同剂量骨水泥灌注单侧经皮椎体成形术治疗骨质疏松性胸腰椎压缩性骨折的临床疗效  

Clinical Efficacy of Unilateral Percutaneous Vertebroplasty with Different Doses of Bone Cement Perfusion in the Treatment of Osteoporotic Thoracolumbar Vertebral Compression Fractures

作　　者：姜明 JIANG Ming(Emergency Department of Guangxin District People's Hospital,Shangrao 334100,Jiangxi,China)

机构地区：[1]上饶市广信区人民医院急诊科,江西上饶334100

出　　处：《医学信息》2023年第21期70-73,共4页Journal of Medical Information

基　　金：江西省卫生健康委科技计划项目(编号:SKJP220200581)。

摘　　要：目的研究不同剂量骨水泥灌注单侧经皮椎体成形术治疗骨质疏松性胸腰椎压缩性骨折的临床疗效。方法选取2021年1月-2022年12月我院诊治的68例骨质疏松性胸腰椎压缩性骨折患者为研究对象,采用随机数字表法分为对照组和观察组,各34例。对照组骨水泥灌注量为多量(2.6~3.5 ml),观察组骨水泥灌注为少量(1.5~2.5 ml),比较两组VAS评分、功能障碍指数(ODI)、椎体前缘高度比、Cobb角、骨水泥渗漏发生率以及并发症发生率。结果两组术后1、3个月VAS评分低于术前,而观察组术后1个月VAS评分高于对照组(P<0.05),但两组术后3个月VAS评分比较,差异无统计学意义(P>0.05)。两组术后1、3个月ODI评分低于术前(P<0.05),但观察组与对照组术后1、3个月ODI评分比较,差异无统计学意义(P>0.05)。两组术后1、3个月椎体前缘高度比大于术前,Cobb角小于术前(P<0.05),而观察组术后1个月椎体前缘高度比小于对照组、Cobb角大于对照组(P<0.05),但两组术后3个月椎体前缘高度比、Cobb角比较,差异无统计学意义(P>0.05)。观察组骨水泥渗漏总发生率为5.88%,低于对照组的14.71%(P<0.05)。两组并发症总发生率比较,差异无统计学意义(P>0.05)。结论不同剂量骨水泥灌注单侧经皮椎体成形术治疗骨质疏松性胸腰椎压缩性骨折均具有一定疗效,可减轻疼痛、改善功能障碍、增大椎体前缘高度比、减小Cobb角,但少量(1.5~2.5 ml)骨水泥注入可降低渗漏发生率。Objective To study the clinical efficacy of unilateral percutaneous vertebroplasty with different doses of bone cement perfusion in the treatment of osteoporotic thoracolumbar vertebral compression fractures.Methods A total of 68 patients with osteoporotic thoracolumbar vertebral compression fractures treated in our hospital from January 2021 to December 2022 were selected as the research objects.They were divided into control group and observation group by random number table method,with 34 patients in each group.The control group had a large amount of bone cement perfusion(2.6-3.5 ml),and the observation group had a small amount of bone cement perfusion(1.5-2.5 ml).The VAS score,dysfunction index(ODI),vertebral height ratio,Cobb angle,bone cement leakage rate and complication rate were compared between the two groups.Results The VAS scores of the two groups at 1 and 3 months after operation were lower than those before operation,while the VAS score of the observation group at 1 month after operation was higher than that of the control group(P<0.05),but there was no significant difference in VAS score between the two groups at 3 months after operation(P>0.05).The ODI score of the two groups at 1 and 3 months after operation was lower than that before operation(P<0.05),but there was no significant difference in ODI scores between the two groups at 1 and 3 months after operation(P>0.05).The anterior vertebral height ratio of the two groups at 1 and 3 months after operation was higher than that before operation,and the Cobb angle was lower than that before operation(P<0.05),while the anterior vertebral height ratio of the observation group at 1 month after operation was lower than that of the control group,and the Cobb angle was higher than that of the control group(P<0.05),but there was no significant difference in the anterior vertebral height ratio and Cobb angle between the two groups at 3 months after operation(P>0.05).The total incidence of bone cement leakage in the observation group was 5.88%,which was lowe

关 键 词：骨水泥灌注 单侧经皮椎体成形术 骨质疏松 胸腰椎压缩性骨折 

分 类 号：R687.3[医药卫生—骨科学]