右美托咪定对老年高血压全身麻醉诱导气管插管应激反应的影响  

Effect of Dexmedetomidine on Stress Response to Tracheal Intubation Induced by General Anesthesia in Middle-aged and Elderly Patients with Hypertension

作　　者：王煜 WANG Yu(Department of Anesthesiology,Pingxiang Xiangdong District People's Hospital,Pingxiang 337016,China)

机构地区：[1]萍乡市湘东区人民医院麻醉科,江西萍乡337016

出　　处：《中国医药指南》2023年第29期101-103,共3页Guide of China Medicine

摘　　要：目的 探讨右美托咪定对老年高血压全身麻醉诱导气管插管应激反应的影响。方法 选取萍乡市湘东区人民医院2021年5月至2022年12月老年高血压全身麻醉诱导气管插管患者50例,采用随机数字表法将其分为对照组25例与研究组25例。对照组患者行常规全身麻醉诱导气管插管,研究组行常规全身麻醉诱导气管插管的基础上复合右美托咪定。比较两组给药后5 min、麻醉后0.5 h、麻醉后2 h血压监测结果、心室率水平、血氧饱和度、恢复自主呼吸时间、苏醒质量评分、苏醒期躁动、呛咳发生率等情况。结果 研究组患者在给药后5 min、麻醉后0.5 h、麻醉后2 h血压监测结果、心室率水平、血氧饱和度,与对照组患者相比,收缩压、舒张压、心室率水平显著降低(P <0.05),而血氧饱和度无明显变化(P> 0.05)。研究组恢复自主呼吸时间短于对照组,苏醒质量评分高于对照组(P <0.05)。研究组苏醒期躁动、呛咳发生率低于对照组(P <0.05)。结论 老年高血压全身麻醉诱导气管插管患者给予右美托咪定效果确切,可有效减轻全身麻醉诱导气管插管应激反应,提高苏醒质量,减少并发症。Objective To investigate the effect of dexmedetomidine on stress response to tracheal intubation induced by general anesthesia in middle-aged and elderly patients with hypertension.Methods From May 2021 to December 2022,50 elderly patients with hypertension undergoing tracheal intubation under general anesthesia in Pingxiang Xiangdong District People's Hospital were selected and divided into a control group of 25 cases and a study group of 25 cases using a random number table method.Patients in the control group were treated with conventional general anesthesia induced tracheal intubation,while patients in the study group were treated with dexmedetomidine on the basis of conventional general anesthesia induced tracheal intubation.The blood pressure monitoring results,ventricular rate levels,blood oxygen saturation,time to resume spontaneous respiration,recovery quality score,and the incidence of restlessness and cough during recovery were compared between the two groups 5 minutes after administration,0.5 hours after anesthesia,and 2 hours after anesthesia.Results Compared with the blood pressure monitoring results,ventricular rate levels,and blood oxygen saturation of patients in the control group at 5 minutes after administration,0.5 hours after anesthesia,and 2 hours after anesthesia,the systolic blood pressure,diastolic blood pressure,ventricular rate levels,and blood oxygen saturation of patients in the study group significantly decreased(P<0.05),while there was no significant change in blood oxygen saturation(P>0.05).The recovery time of spontaneous breathing in the study group was shorter than that in the control group,and the quality of recovery score was higher in the study group than in the control group(P<0.05).The incidence of restlessness and cough in the study group during the recovery period was lower than that in the control group(P<0.05).Conclusions The effect of dexmedetomidine given to middle-aged and elderly hypertensive patients with tracheal intubation induced by general anesthesia is accurat

关 键 词：右美托咪定 老年高血压 全身麻醉诱导气管插管应激反应 影响 

分 类 号：R544.1[医药卫生—心血管疾病]