重症监护病房床旁病原学快速诊断-快速现场微生物学评价  

Rapid on-site pathogen diagnosis of intensive care unit: Microbiological Rapid On-Site Evaluation

作　　者：王秀丽[1] 王凯飞[1] 解立新[1] Wang Xiuli;Wang Kaifei;Xie Lixin(College of pulmonary and Critical Care Medicine,Chinese PLA General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院呼吸与危重症医学部,解放军医学院,北京100853

出　　处：《中华检验医学杂志》2023年第10期997-1002,共6页Chinese Journal of Laboratory Medicine

基　　金：首都卫生发展科研专项(2022-1-5091);北京市自然科学基金面上项目(7222181)。

摘　　要：脓毒症相关死亡占全球总死亡人数比例超过50%, 是威胁公共卫生健康的首要问题。血培养是临床常用确诊脓毒症的方法, 然而其耗时长、易受抗菌药物影响, 尚无法满足快速明确病原的需求。快速现场微生物学评价技术(M-ROSE)是有效快速诊断的方法之一。作为呼吸感染性疾病诊断的辅助手段, M-ROSE在评价标本质量、辅助诊断感染病原、动态监测疗效等方面具有显著优势, 能够助力脓毒症患者的早期病原学诊断。在临床中应密切结合实际情况, 实现M-ROSE效益最大化。Sepsis-related deaths account for more than 50%of the total deaths in the world and are the primary problem threatening public health.Timely and rapid diagnosis is the key to improving the survival rate of patients with sepsis.Blood culture is a commonly used method to diagnose sepsis in clinics.However,it is time-consuming and unstable,which cannot used for pathogen quickly identification.In recent years,Microbiological rapid on-site evaluation(M-ROSE)based on morphological technique is applying to the clinics,showing significant advantages in timeliness and convenience,which would overcome the shortcomings of traditional diagnostic methods and be conducive to diagnosis of sepsis.

关 键 词：脓毒症 实验室诊断 微生物 M-ROSE 

分 类 号：R459.7[医药卫生—急诊医学]