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作 者:冯丽萍 朱琦 林金杏 FENG Liping;ZHU Qi;LIN Jinxing(Shanghai Laboratory Animal Research Center,Shanghai 201203,China)
出 处:《实验动物与比较医学》2023年第5期524-530,共7页Laboratory Animal and Comparative Medicine
基 金:上海市科技计划项目“上海市水生实验动物专业技术服务平台”(22DZ2291200);上海实验动物研究中心科技创新计划新星项目“新发肠道细菌丹尼链球菌特性及其检测方法的研究”(2023NS02)。
摘 要:近年来,随着生命科学的高速发展,实验用鱼在毒理学、遗传学、发育生物学和医学等研究中的使用量大幅增加,逐渐成为重要的新型模式生物。与此同时,实验用鱼的福利问题也日益得到关注。尽管与陆生实验动物相比,实验用鱼福利的研究水平还处于相对早期阶段,但欧美等发达国家已经建立了相应的法律法规,以保障实验用鱼在研究中的福利。本文阐述了实验用鱼福利研究的发展现状,讨论需要重视和提高福利的原因,从饲养阶段和实验阶段两方面深入探究影响福利的因素,并探索提高福利的对策,旨在促进我国实验用鱼福利的不断提升。In recent years,with the rapid development of life sciences,the use of laboratory fish in toxicology,genetics,developmental biology and medicine has increased dramatically,and they have gradually become important new model organisms.At the same time,the welfare of laboratory fish has also received increasing attention.Although the research level of experimental fish welfare is still in a relatively early stage compared to terrestrial experimental animals,developed regions such as Europe and America have established corresponding legal frameworks to safeguard the welfare of laboratory fish in research.This article elucidates the current developmental status of laboratory fish welfare,discusses the rationale behind the imperative to prioritize and enhance their welfare,deeply investigates factors influencing their welfare from the feeding stage and experimental stage.Moreover,it explores strategies for augmenting welfare standards,with the overarching aim of propelling the continual improvement of laboratory fish welfare in our country.
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