补气活血方联合火龙罐治疗寒湿痹阻证腰椎间盘突出症临床研究  

Clinical Study on Buqi Huoxue Prescription Combined with Huolong Cupping for Lumbar Disc Herniation with Cold-Damp Obstruction Syndrome

作　　者：傅娟 陈秋婉 王凌燕 范旭莉 FU Juan;CHEN Qiuwan;WANG Lingyan;FAN Xuli(Department of Rehabilitation Medicine,Jinhua Hospital of Traditional Chinese Medicine,Jinhua Zhejiang 321017,China;Department of Nursing,Jinhua Hospital of Traditional Chinese Medicine,Jinhua Zhejiang 321017,China)

机构地区：[1]金华市中医医院康复医学科,浙江金华321017 [2]金华市中医医院护理部,浙江金华321017

出　　处：《新中医》2023年第18期77-81,共5页New Chinese Medicine

摘　　要：目的:观察补气活血方联合火龙罐治疗寒湿痹阻证腰椎间盘突出症(LDH)的临床疗效。方法:选取LDH患者90例,按随机数字表法分为对照组与观察组各45例。研究过程中,对照组失访2例,最终完成43例;观察组未按要求服药2例,失访1例,最终完成42例。对照组给予塞来昔布胶囊口服,观察组给予补气活血方联合火龙罐治疗。2组均连续治疗4周,比较2组临床疗效和不良反应发生率,2组治疗前后疼痛视觉模拟评分法(VAS)、腰痛日本骨科学会(JOA)评分和Oswestry功能障碍指数(ODI)、匹兹堡睡眠质量指数(PSQI)、健康调查简表(SF-36)评分,以及血清β-内啡肽(β-EP)、前列腺素E2(PGE2)水平。结果:观察组总有效率为95.24%,对照组79.07%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组VAS、ODI评分均较治疗前降低(P<0.05),JOA评分较治疗前增高(P<0.05);且观察组VAS、ODI评分低于对照组(P<0.05),JOA评分高于对照组(P<0.05)。治疗后,2组PSQI评分均较治疗前降低(P<0.05),SF-36评分均较治疗前升高(P<0.05);且观察组PSQI评分低于对照组(P<0.05),SF-36评分高于对照组(P<0.05)。治疗后,2组血清β-EP水平较治疗前升高(P<0.05),PGE2水平较治疗前降低(P<0.05);且观察组β-EP水平高于对照组(P<0.05),PGE2水平低于对照组(P<0.05)。观察组不良反应发生率为4.76%,对照组为27.91%,2组比较,差异有统计学意义(P<0.05)。结论:补气活血方联合火龙罐治疗寒湿痹阻证LDH能够明显缓解疼痛症状,改善腰椎功能,提高患者睡眠质量和生活质量,且安全性良好。Objective:To observe the clinical effect of Buqi Huoxue Prescription combined with Huolong Cupping for lumbar disc herniation(LDH) with cold-damp obstruction syndrome.Methods:A total of90 cases of LDH patients were selected and divided into the control group and the observation group according to the random number table method,with 45 cases in each group.During the research,2 cases lost follow-up in the control group,and finally,43 cases completed the process;in the observation group,2 cases did not take medicine as required and 1 case lost follow-up,and finally,42 cases completed the research.The control group was treated with the oral administration of Celecoxib Capsules,and the observation group was treated with Buqi Huoxue Prescription combined with Huolong Cupping.Both groups were continuously treated for four weeks.Clinical effects and the incidence of adverse reactions were compared between the two groups.The scores of Visual Analogue Scale(VAS) for pain,Japanese Orthopaedic Association(JOA),Oswestry Disability Index(ODI),Pittsburgh Sleep Quality Index(PSQI),and 36-Item Short Form Survey(SF-36),as well as the levels of β-endorphin(β-EP) and prostaglandin E2(PGE2) were compared before and after treatment between the two groups.Results:The total effective rate was 95.24% in the observation group and 79.07% in the control group,the difference being significant(P<0.05).After treatment,the scores of VAS and ODI in the two groups were decreased when compared with those before treatment(P<0.05),and JOA scores were increased when compared with those before treatment(P<0.05);the scores of VAS and ODI in the observation group were lower than those in the control group(P<0.05),and JOA score in the observation group was higher than that in the control group(P<0.05).After treatment,the PSQI scores in the two groups were decreased when compared with those before treatment(P<0.05),and SF-36 scores were increased when compared with those before treatment(P<0.05);the PSQI score in the observation group was lower than tha

关 键 词：腰椎间盘突出症 补气活血方 火龙罐 腰椎功能 Β-内啡肽 前列腺素E2 

分 类 号：R681.53[医药卫生—骨科学]