正骨推拿治疗单纯腰椎间盘突出症疗效观察及对血清IL-1β、hs-CRP水平的影响  

Observation on Curative Effect of Orthopedic Tuina for Simple Disc Herniation and Its Effect on Levels of Il-1β And hs-CRP in Serum

作　　者：王雷 WANG Lei(Department of Acupuncture-Moxibustion and Tuina,Daishan County Hospital of Chinese Medicine,Daishan Zhejiang 316000,China)

机构地区：[1]岱山县中医院针灸推拿科,浙江岱山316000

出　　处：《新中医》2023年第18期169-173,共5页New Chinese Medicine

摘　　要：目的:观察正骨推拿治疗单纯腰椎间盘突出症的临床疗效及对血清白细胞介素-1β (IL-1β)、超敏C-反应蛋白(hs-CRP)水平的影响。方法:将166例单纯腰椎间盘突出症患者随机分为对照组和观察组各83例。对照组行常规腰椎牵引治疗,观察组给予正骨推拿治疗。比较2组日本骨科协会评估量表(JOA)评分、疼痛视觉模拟评分法(VAS)评分、血清IL-1β及hs-CRP水平、临床疗效。结果:观察组总有效率为89.16%,对照组为74.70%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组JOA量表中主观症状、临床体征、日常活动受限度评分比较,差异无统计学意义(P>0.05);治疗后,2组主观症状、临床体征、日常活动受限度评分均较治疗前升高(P<0.05),且观察组上述各项评分均高于对照组(P<0.05)。治疗前,2组VAS评分比较,差异无统计学意义(P>0.05);治疗后,2组VAS评分均较治疗前降低(P<0.05),且观察组VAS评分低于对照组(P<0.05)。治疗前,2组血清IL-1β、hs-CRP水平比较,差异无统计学意义(P>0.05);治疗后,2组IL-1β、hs-CRP水平均较治疗前降低(P<0.05),且观察组IL-1β、hs-CRP水平均低于对照组(P<0.05)。结论:正骨推拿治疗单纯腰椎间盘突出症疗效显著,能减轻机体炎症反应,有效改善患者腰椎功能,缓解腰痛症状。Objective:To observe the clinical effect of orthopedic tuina for simple disc herniation and its effect on levels of interleukin-1β(IL-1β) and hypersensitive C-reactive protein(hs-CRP) in serum.Methods:A total of 166 cases of patients with simple disc herniation were randomly divided into the control group and the observation group,with 83 cases in each group.The control group was treated with routine lumbar traction,and the observation group was treated with orthopedic tuina.The Japanese Orthopaedic Association Assessment Scale(JOA) scores,Visual Analogue Scale(VAS) scores of pain,IL-1β levels,hs-CRP levels,and clinical effects were compared between the two groups.Results:The total effective rate was 89.16% in the observation group and 74.70% in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of the scores of subjective symptoms,clinical signs,and limitations on daily activities in JOA scale between the two groups(P>0.05).After treatment,the scores of subjective symptoms,clinical signs,and limitations on daily activities in JOA scale in the two groups were increased when compared with those before treatment(P<0.05),and the above scores in the observation group were higher than those in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of VAS scores between the two groups(P>0.05).After treatment,VAS scores in the two groups were decreased when compared with those before treatment(P<0.05),and VAS score in the observation group was lower than that in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of the levels of IL-1β and hs-CRP in serum between the two groups(P<0.05).After treatment,the levels of IL-1β and hs-CRP in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of IL-1β and hs-CRP in the observation group were lower than those in the control group(P

关 键 词：单纯腰椎间盘突出 正骨推拿 日本骨科协会评估量表 视觉模拟评分法 白细胞介素-1β 

分 类 号：R681.53[医药卫生—骨科学]