罗哌卡因联合利多卡因在永久性心脏起搏器植入术患者中的应用  

Application of Ropivacaine combined with Lidocaine in patients undergoing permanent cardiac pacemaker implantation surgery

作　　者：周亮 钟雯[1] 李丽[1] 李颐[1] 孔欣怡[1] 章际云 ZHOU Liang;ZHONG Wen;LI Li;LI Yi;KONG Xinyi;ZHANG Jiyun(Department of Cardiology,the Second Affiliated Hospital of Nanchang University,Jiangxi Province,Nanchang 330000,China)

机构地区：[1]南昌大学第二附属医院心内科,江西南昌330000

出　　处：《中国当代医药》2023年第30期79-82,共4页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(skjp220203153)。

摘　　要：目的研究分析罗哌卡因联合利多卡因在永久性心脏起搏器术中的镇痛疗效。方法选取2021年5月至2022年10月南昌大学第二附属医院收治的76例行永久性心脏起搏器术治疗患者作为研究对象,采用随机数字表法将其分为观察组(n=38)和对照组(n=38)。观察组采取罗哌卡因联合利多卡因进行局部麻醉,对照组采取利多卡因进行局部麻醉。对比分析两组的镇痛效果。结果观察组术后1、3、6 h的平均动脉压、心率与对照组比较,差异无统计学意义(P>0.05);观察组术后1、3、6h的疼痛评分低于对照组,差异有统计学意义(P<0.05);观察组患者的不良反应总发生率与对照组比较,差异无统计学意义(P>0.05)。结论在永久性心脏起搏器术中,采用罗哌卡因联合利多卡因进行局部麻醉能够有效减轻术后疼痛,且联合用药不会增加不良反应的发生风险,具有较高的安全性。Objective To study and analyze the analgesic efficacy of Ropivacaine combined with Lidocaine in permanent cardiac pacemaker surgery.Methods A total of 76 patients who underwent permanent pacemaker treatment in the Second Affiliated Hospital of Nanchang University from May 2021 to October 2022 were selected as research objects,and they were divided into the observation group(n=38)and the control group(n=38)by random number table method.The observation group received Ropivacaine combined with Lidocaine for local anesthesia,and the control group received Lidocaine for local anesthesia.The analgesic effects of the two groups were compared and analyzed.Results There were no significant differ-ences in the mean arterial pressure and the heart rate between the observation group and the control group at 1,3 and 6 h after operation(P>0.05).The pain scores of the observation group at 1,3 and 6 h after operation were lower than those of the control group,the differences were statistically significant(P<0.05).There was no significant difference in the total in-cidence of adverse reactions between the observation group and the control group(P>0.05).Conclusion In permanent pacemaker surgery,Ropivacaine combined with Lidocaine for local anesthesia can effectively reduce postoperative pain,and the combination of Ropivacaine will not increase the risk of adverse reactions,with higher safety.

关 键 词：罗哌卡因 利多卡因 永久性心脏起搏器术 疼痛 

分 类 号：R614.3[医药卫生—麻醉学]