终末期肾病肾移植术后磁共振神经影像学研究进展  

Recent advances of magnetic resonance neuroimaging after kidney transplantation in patients with end-stage renal disease

作　　者：陈诗桦(综述) 谭理连(审校)[1] CHEN Shihua;TAN Lilian(Department of Radiology,The Second Affiliated Hospital,Guangzhou Medical University,Guangdong 510000,China)

机构地区：[1]广州医科大学附属第二医院放射科,广东广州510000

出　　处：《影像诊断与介入放射学》2023年第5期375-380,共6页Diagnostic Imaging & Interventional Radiology

摘　　要：终末期肾病(ESRD)作为慢性肾脏病的严重转归,常伴随多系统并发症,其中终末期肾病相关的认知障碍是中枢神经病变的主要表现。肾移植作为肾脏替代治疗的重要手段,能有效改善ESRD患者的认知障碍。了解肾移植前后脑部相关变化有助于阐明术后ESRD患者认知障碍潜在可逆性的机制。神经影像学是探究认知损伤潜在机制的有效手段,多模态磁共振成像的深入应用可从脑结构及功能改变的角度提供客观的神经影像学线索。本文对肾移植术后ESRD患者神经影像磁共振成像研究进展进行综述。End-stage renal disease(ESRD)is often accompanied by multi-system complications including central neuropathy manifested mainly as cognitive impairment.Kidney transplantation can improve the cognitive impairment.Understanding the brain changes before and after kidney transplantation will help to clarify the mechanism of potential reversibility of cognitive impairment.Multimodal magnetic resonance neuroimaging can assess brain structure and function changes.This article reviews the recent advances of magnetic resonance neuroimaging in patients with ESRD after kidney transplantation.

关 键 词：肾移植 终末期肾病 磁共振成像 认知障碍 

分 类 号：R692.5[医药卫生—泌尿科学] R445.2[医药卫生—外科学] R742[医药卫生—临床医学]