供体-受体氮杂环丙烷碳-碳键断裂的环加成反应研究进展  

Recent Advances in Cycloaddition Reactions of Donor-Acceptor Aziridines via Carbon-Carbon Bond Cleavage

作　　者：陈祖良 魏颖静 张俊良 Chen Zuliang;Wei Yingjing;Zhang Junliang(College of Chemistry and Bio-engineering,Yichun University,Yichun,Jiangxi 333600;Department of Chemistry,Fudan University,Shanghai 200438)

机构地区：[1]宜春学院化学与生物工程学院,江西宜春336000 [2]复旦大学化学系,上海200438

出　　处：《有机化学》2023年第9期3078-3088,共11页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(21861041)。

摘　　要：氮杂环丙烷有两种不同的开环方式: 一种是碳-氮键断裂开环, 另一种是碳-碳键断裂开环. 其中, 氮杂环丙烷以碳-氮键断裂的反应已经有很多综述报道. 主要概述了近二十年来供体-受体(Donor-Acceptor, D-A)氮杂环丙烷以碳-碳键断裂的环加成反应研究进展. 在合适催化剂作用下, D-A氮杂环丙烷经碳-碳键断裂开环形成亚胺叶立德, 该叶立德可以和醛、亚胺、烯烃、炔烃和吲哚等发生[3+n]环加成反应.There are two different ring-opening modes of aziridines: ring-opening of aziridines via carbon-nitrogen bond cleavage, and ring-opening of aziridines via carbon-carbon bond cleavage. Among them, the reaction of aziridines via carbon-nitrogen bond cleavage has been reported in many reviews. The cycloaddition reactions of donor-acceptor (D-A) aziridines via carbon-carbon bond cleavage in recent 20 years are mainly summarized. Under some proper catalysts, the ring-opening of D-A aziridines via carbon-carbon bond cleavage yield azomethine ylides, which can undergo [3+n] cycloaddition reaction with aldehydes, imines, alkenes, alkynes, indoles etc.

关 键 词：D-A氮杂环丙烷 碳-碳键断裂 环加成反应 亚胺叶立德 

分 类 号：O621.25[理学—有机化学]