MOFs基纳米酶的生物传感应用研究  

Research and application on MOFs-based nanozyme biosensors

作　　者：罗姣 梁冰 郭佳豪 李君[1] 吴玲[1] 肖忠良[1] 于冬宏[2] 曹忠[1] Luo Jiao;Liang Bing;Guo Jia-hao;Li Jun;Wu Ling;Xiao Zhong-liang;Yu Dong-hong;Cao Zhong(Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation&Hunan Provincial Key Laboratory of Cytochemistry,School of Chemistry and Chemical Engineering,Changsha University of Science and Technology,Changsha 410114,China;Department of Chemistry and Bioscience,Aalborg University,DK-9220 Aalborg,Denmark)

机构地区：[1]长沙理工大学化学化工学院,电力与交通材料保护湖南省重点实验室,细胞化学湖南省重点实验室,湖南长沙410114 [2]奥尔堡大学化学与生物科学系,丹麦奥尔堡DK-9220

出　　处：《化学传感器》2023年第1期36-45,共10页Chemical Sensors

基　　金：国家自然科学基金(No.31527803);湖南省自然科学基金(No.2020JJ4559);湖南省教育厅科学研究项目(Nos.21A0182,21C0195);长沙理工大学研究生科研创新项目(No.CX2021SS79)。

摘　　要：MOFs基纳米酶因其自身具有较高的原子利用率、独特的几何和电子结构,在催化反应中表现出更高的催化活性,目前已经成为纳米酶研究的热点。在该文中,总结了MOFs基纳米酶的分类及其在生物传感领域的应用进展,并对比了基于不同MOFs基纳米酶传感器的构建及其检测性能,阐明了MOFs基纳米酶应用的前景和面临的挑战,旨在为MOFs基纳米酶的发展提供参考。MOFs-based nanozymes are currently a hot topic in nanozyme research field,as they exhibit higher catalytic activity and specificity in catalytic reactions because of their own maximum atom utilization,well-defined geometrical and electronic structures.In this paper,we summarized the classification of MOFs-based nanozymes and the progress of their applications in biosensing.We also compared the construction of different MOFsbased nanosensors and their detection performance,and clarified the prospects and challenges of MOFs-based nanosensors'applications,aiming to provide a reference for the development of MOFs-based nanozymes.

关 键 词：MOFs基纳米酶 纳米材料 生物传感 分析应用 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置]