Research Progress on Mechanism of Ovulation Disorder in Polycystic Ovary Syndrome  

作　　者：Li HUANG Chong ZHOU 

机构地区：[1]Guangxi University of Chinese Medicine,Nanning 530200,Guangxi

出　　处：《Agricultural Biotechnology》2023年第5期83-87,共5页农业生物技术(英文版)

基　　金：Supported by Guangxi Natural Science Foundation (2020GXNSFAA238022);National Natural Sciences Foundation of China (82060280);Doctoral Research Start-up Fund of Guangxi University of Chinese Medicine (2017BS011);Science and Technology Plan Project of Guangxi University of Chinese Medicine (2018ZD003).

摘　　要：Polycystic ovary syndrome(PCOS)is a reproductive endocrine disease characterized by ovulation disorder,hyperandrogenism and/or polycystic ovary.Follicular development disorder caused by PCOS accounts for up to 75%of anovulatory infertility,which is a common cause of infertility and affects up to 15%of reproductive aged women worldwide.Oxidative stress,chronic inflammation,endoplasmic reticulum stress and other pathological conditions coexist in the ovarian microenvironment of PCOS,which are further aggravated under the action of high levels of androgens,synergistically deteriorating the follicular microenvironment,leading to ovulation disorders in PCOS patients.This paper briefly reviewed the research on the mechanism of PCOS ovulation disorder in recent years.

关 键 词：Polycystic ovary syndrome Ovulation disorders Research progress 

分 类 号：Q948[生物学—植物学]