闽南地区某部队幽门螺杆菌感染及基因型分布情况  

Investigation and analysis of Helicobacter pylori infection and genotype distribution in a military unit in southern Fujian

作　　者：郑媛媛 胡团敏 ZHENG Yuanyuan;HU Tuanmin(Department of Gastrology,the 910th Hospital of the Joint Logistics Suppot Force PLA,Quanzhou 362000,Fujian,China)

机构地区：[1]解放军联勤保障部队第九一〇医院消化内科,泉州362000

出　　处：《医学研究与战创伤救治》2023年第6期604-608,共5页Journal of Medical Research & Combat Trauma Care

摘　　要：目的探讨闽南地区某部队幽门螺杆菌(Hp)感染及其基因型分布情况,并分析其相关因素。方法2016年12月间对某部队官兵进行Hp流行病学调查,采用整体随机抽样方式抽查202名官兵作为纳入对象,根据职别分为士兵组(n=150,作训士兵、炊事员及驾驶员)、军官组(n=52,地勤干部及飞行员)。采用问卷调查方式收集纳入对象年龄、职别、职业及疾病史等资料,并抽血检测纳入对象的Hp抗体及其基因型,分析Hp抗体阳性患者在职别、部门及年龄等方面分布情况,采用Logistics回归分析影响患者感染的相关因素。结果总体Hp抗体阳性率为31.68%,军官阳性率为44.23%,士兵阳性率为27.33%。军官组Hp抗体阳性率明显高于士兵组(P<0.05)。部队官兵Hp感染以I型Hp感染为主,其中士兵组I型Hp抗体阳性率(56.1%)高于II型Hp抗体阳性率(43.9%),差异有统计学意义(P<0.05)。军官组I型Hp抗体阳性率(78.26%)较II型(21.74%)明显升高(P<0.05)。飞行员I型Hp抗体阳性率明显高于其它(P<0.05)。20~29岁Hp抗体阳性率明显高于其他年龄段(P<0.05)。Logistics分析结果得出,经常食用咸菜、使用公筷、有胃癌家族史及有慢性胃炎病史均为影响患者感染的主要因素(P<0.05)。结论闽南地区某陆航部队Hp感染率军官高于士兵,其中飞行人员I型Hp抗体阳性率更高,针对感染现状及经常食用咸菜、使用公筷、有胃癌家族史及有慢性胃炎病史的危险因素,应制定合理有效防治措施。Objective To investigate Helicobacter pylori(Hp)infection and its genotypes distribution in a military unit in southern Fujian and to analyze its related factors.Methods In December 2016,an Hp epidemiological survey was conducted among officers and soldiers of a certain unit,and 202 officers and soldiers were randomly selected as the research subjects.According to their positions,they are divided into a soldier group(n=150,training soldiers,cooks and pilots)and an officer group(n=52,ground staff and pilots).A questionnaire survey was adopted to collect information on the age,occupation,position and disease history of the research subjects,and Hp antibodies and genotypes were detected in the blood test.The distribution of Hp antibody-positive patients in terms of occupation,department,age,etc.,and Logistics regression was used to analyze the related factors affecting patient infection.Results The overall Hp antibody positivity rate was 31.68%,the positivity rate for officers 44.23%,and the positivity rate for soldiers 27.33%.Hp infection among army officers and soldiers was mainly type I Hp infection.In the soldier group,the positive rate of type I Hp antibody(56.1%)was higher than the positive rate of type II Hp antibody(43.9%),and the difference is statistically significant(P<0.05).In the officer group,the positive rate of type I Hp antibody(78.26%)was significantly higher than that of type II(21.74%)(P<0.05).In pilots,the positive rate of type I Hp antibody was significantly higher than that in others(P<0.05).The positive rate of Hp antibody in those aged 20-29 years was significantly higher than that in other age groups(P<0.05).Logistics analysis result showed that frequent consumption of pickles,use of serving chopsticks,family history of gastric cancer and history of chronic gastritis were the main affecting factors.Conclusion Hp infection rate of officers was higher than that of soldiers in an army aviation unit in southern Fujian.Among them,the positive rate of type I Hp antibodies among pilots is higher.B

关 键 词：闽南地区 陆航部队 幽门螺杆菌 基因型 相关因素 

分 类 号：R51[医药卫生—内科学]