冠心病心绞痛患者发生急性心血管事件的相关因素  

Related Factors of Acute Cardiovascular Events in Patients with Coronary Heart Disease and Angina Pectoris

作　　者：王朝菊[1] 吴登轩 冉梦念 WANG Chaoju;WU Dengxuan;RAN Mengnian(Panzhihua Central Hospital,Panzhihua 617067,China;不详)

机构地区：[1]攀枝花市中心医院,四川攀枝花617067

出　　处：《中外医学研究》2023年第29期152-157,共6页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析冠心病心绞痛(CHD-AP)患者发生急性心血管事件的相关影响因素。方法:选择2020年4月—2022年4月于攀枝花市中心医院心血管内科检查的395例CHD-AP患者作为研究对象。对患者进行为期3个月的随访,将出现急性心血管事件的患者作为观察组(n=52),未出现急性心血管事件的患者作为对照组(n=343)。采用问卷调查的方式收集CHD-AP的一般资料并进行比较,采用logistic多因素回归分析此类患者发生急性心血管事件的影响因素。结果:395例CHD-AP中,发生急性心血管事件共计52例,占比为13.16%。其中恶性室性心律失常8例(15.38%),急性心肌梗死27例(51.92%),心力衰竭16例(30.77%),心源性猝死1例(1.92%);单因素分析显示,患者性别、饮酒与CHD-AP患者发生急性心血管事件无关(P>0.05);年龄≥65岁、肥胖、吸烟史、心率≥80次/min、高脂血症、高血压、糖尿病、肌钙蛋白T(cTnT)升高、超敏C反应蛋白(hs-CRP)升高、B型钠尿肽前体(pro-BNP)升高、未行有创干预、冠心病家族史与CHD-AP患者发生急性心血管事件有关(P<0.05);对差异有统计学意义的单因素进行多因素logistic回归分析,结果显示年龄≥65岁、肥胖、有吸烟史、心率≥80次/min、合并高脂血症、合并高血压、合并糖尿病、cTnT升高、pro-BNP升高、hs-CRP升高、未行有创干预、有冠心病家族史是CHD-AP患者发生急性心血管事件的独立影响因素(P<0.05)。结论:影响CHD-AP患者发生急性心血管事件的因素较多,因此临床在治疗此病时应当坚持个性化治疗原则,合理评估危险因素,并给予针对性干预,以减少急性心血管事件发生。Objective:To analyze the related influencing factors of acute cardiovascular events in patients with coronary heart disease and angina pectoris(CHD-AP).Method:A total of 395 patients with CHD-AP who were examined in the Department of Cardiovascular Medicine of Panzhihua Central Hospital from April 2020 to April 2022 were selected as the study subjects.Patients were followed up for 3 months.The patients with acute cardiovascular events were taken as the observation group(n=52),and the patients without acute cardiovascular events were taken as the control group(n=343).A questionnaire survey was used to collect and compare general data on CHD-AP,multivariate logistic regression was used to analyze the influencing factors of acute cardiovascular events in these patients.Result:Among the 395 cases of CHD-AP,a total of 52 cases(13.16%)experienced acute cardiovascular events.Among them,there were 8 cases(15.38%)of malignant ventricular arrhythmia,27 cases(51.92%)of acute myocardial infarction,16 cases(30.77%)of heart failure,and 1 case(1.92%)of sudden cardiac death.Univariate logistic analysis showed that sex and alcohol consumption were not associated with acute cardiovascular events in patients with CHD-AP(P>0.05).Age≥65 years old,obesity,smoking history,heart rate≥80 times/min,hyperlipidemia,hypertension,diabetes,elevated troponin T(cTnT),elevated hypersensitive C-reactive protein(hs-CRP),elevated B-type natriuretic peptide precursor(pro-BNP),no invasive intervention,and family history of coronary heart disease were associated with acute cardiovascular events in patients with CHD-AP(P<0.05).Multivariate logistic regression analysis of single factors with significant influence showed that age≥65 years old,obesity,smoking history,heart rate≥80 times/min,hyperlipidemia,hypertension,diabetes,elevated cTnT,elevated pro-BNP,elevated hs-CRP,no invasive intervention,and family history of coronary heart disease were independent factors influencing the occurrence of acute cardiovascular events in patients with angina p

关 键 词：冠心病 心绞痛 急性心血管事件 危险因素 对策 

分 类 号：R541.4[医药卫生—心血管疾病]