机构地区:[1]成都中医药大学附属医院,四川成都610075 [2]成都中医药大学,四川成都610072
出 处:《四川中医》2023年第9期108-112,共5页Journal of Sichuan of Traditional Chinese Medicine
基 金:四川省中医药管理局科学技术研究专项课题(编号:NO.2021MS068);四川省科技厅重点研发项目(编号:NO.2021YSF0275);中国民族医学药会科研项目(编号:2019K+YXM-Z1120-81)。
摘 要:目的:观察“针药联用”治疗肛门湿疹(血虚风燥型)的临床疗效。方法:选取2021年12月-2022年06月期间就诊于成都中医药大学附属医院肛肠科门诊并诊断为肛门湿疹(血虚风燥型)的60例患者,采用随机数字表法将其分为观察组与对照组,每组30例。观察组:肛周皮损毫火针点刺(每周一、周四)治疗后,薄涂(0.2g/cm^(2))曲安奈德益康唑乳膏(1次/天,使用一周,暂停一周)。对照组:仅予以肛周皮损处薄涂(0.2g/cm^(2))曲安奈德益康唑乳膏(方法同观察组)。两组患者均连续治疗四周,并对治疗前后瘙痒程度、皮损面积、皮损形态及焦虑自评量表(SAS)、抑郁自评量表(SDS)、心理弹性量表(CD-RISC)评分对比。结果:治疗前,对照组与观察组间瘙痒程度、皮损面积、皮损形态、心理状态(SAS、SDS、CD-RISC)评分无明显统计学意义差异(P>0.05);治疗后,两组患者瘙痒程度、皮损面积、皮损形态、SAS及SDS评分均较治疗前降低,CD-RISC评分均较治疗前升高,但在治疗效果上,观察组评分均显著优于对照组,差异具有统计学意义(P<0.05)。半年后门诊随访,对照组中有11(36.67%)名患者复发,观察组有2(6.67%)名患者复发。结论:采用毫火针点刺配合曲安奈德益康唑乳膏外擦治疗肛门湿疹(血虚风燥型),可缓解患者瘙痒程度,改善患者皮损面积及皮损形态,改善焦虑、抑郁等不良情绪,提高患者心理弹性水平,达到身心同治目的,为临床治疗提供新方法。OBJECTIVE:To observe the clinical efficacy of“needle-medicine combination”(milli-fire acupuncture combined with trimethoprim econazole cream topical use)in the treatment of anal eczema(blood deficiency and wind dryness type).METHODS:60patients who were diagnosed with anal eczema(blood deficiency and wind dryness type)attended the outpatient clinic of Anorectal Department of the Hospital of Chengdu University of Traditional Chinese Medicine from December 2021to June 2022were divided into a control group and an observation group by using the random number table method,with 30cases in each group.Control group:thinly applied(0.2g/cm^(2))trimethoprim econazole cream on the perianal lesions once a day for a week with one one-week suspension.Based on the control group's treatment,the observation group performed milli-fire acupuncture twice a week(Monday and Thursday).Patients in both groups were treated for four consecutive weeks as a course of treatment.The degree of itching,lesion area,lesion morphology,self-rating anxiety scale(SAS),self-rating depression scale(SDS)and Connor-Davidson resilience scale(CD-RISC)scores were compared before and after treatment.RESULTS:Before treatment,there was no statistically significant difference between the control group and the observation group in terms of itching degree,lesion area,lesion morphology,and psychological state(SAS,SDS,and CD-RISC)scores(P 0.05);after treatment,the itching degree,lesion area,lesion morphology,SAS and SDS scores decreased,and the CD-RISC scores increased in both groups.It is worth noting that,in terms of treatment effect,the scores of the observation group were significantly better than those of the control group,and the difference was significant(P<0.05).After six months of outpatient follow-up,11(36.67%)patients in the control group and 2(6.67%)patients in the observation group had a recurrence.Conclusion:The treatment of anal eczema(blood deficiency and wind dryness type)by using milli-fire acupuncture with external use of trimethoprim econazole
关 键 词:针药联用 毫火针 曲安奈德益康唑乳膏 肛门湿疹(血虚风燥型)
分 类 号:R758.23[医药卫生—皮肤病学与性病学]
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