五积散治疗脾虚痰湿型多囊卵巢综合征疗效分析  

Effect of Wuji Powder on Polycystic Ovarian Syndrome of Phlegm-dampness Due to Deficiency of the Spleen Syndrome

作　　者：许佳 章靖一[1] 陆新筠 XU Jia;ZHANG Jingyi;LU Xinyun(Department of Gynecology,Jiangyin People's Hospital,Jiangyin Jiangsu 214400,China)

机构地区：[1]江阴市人民医院妇科,江苏江阴214400

出　　处：《四川中医》2023年第9期175-178,共4页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:探讨五积散治疗脾虚痰湿型多囊卵巢综合征(PCOS)的临床疗效。方法:将2021年1月~2022年6月期间至我院生殖内分泌门诊就诊的84例脾虚痰湿型PCOS患者按随机数字表法分为两组,对照组42例采用常规药物治疗,观察组42例在常规治疗基础上给予五积散治疗。比较治疗前、治疗后性激素水平、糖代谢、脂代谢、卵巢体积与卵泡数目以及综合疗效。结果:治疗后两组促黄体生成激素(LH)、睾酮(T)、卵泡刺激素(FSH)水平显著降低,雌二醇(E_(2))水平显著升高,且观察组治疗后效果优于对照组(P<0.05);治疗后两组糖化血红蛋白(HbA1c)、胰岛素抵抗指数(HOMA-IR)、甘油三脂(TG)、总胆固醇(TC)均显著降低,且观察组治疗后均低于对照组(P<0.05);治疗后两组卵泡数目、两侧卵巢体积均显著降低,且观察组治疗后显著低于对照组(P<0.05);观察组治疗总有效率显著高于对照组(P<0.05)。结论:五积散治疗脾虚痰湿型PCOS能够有效调节患者性激素水平以及糖脂代谢,改善多囊样改变,提升临床疗效。Objective To explore the clinical effect of Wuji Powder on polycystic ovary syndrome(PCOS)of phlegm-dampness due to deficiency of the spleen syndrome.Methods 84patients with PCOS of phlegm-dampness due to deficiency of the spleen syndrome were randomly divided into two groups.42cases in the control group were treated with conventional medicine,42cases in the observation group were treated with Wuji Powder based on conventional treatment.The levels of sex hormones,glucose metabolism,lipid metabolism,ovarian volume,follicle number and comprehensive efficacy were compared before and after treatment.Results After treatment,the levels of luteinizing hormone(LH),testosterone(T)and follicle stimulating hormone(FSH)were significantly reduced in both groups,and the observation group was lower than the control group(P<0.05);After treatment,HbA1c,HOMA-IR,TG and TC iwere significantly reduced in the two groups after treatment,and the observation group were lower than those in the control group(P<0.05);After treatment,the number of follicles and the volume of bilateral ovaries in the two groups were significantly reduced,and the number of follicles in the observation group was significantly lower than that in the control group(P<0.05);The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).Conclusion Wuji Powder can effectively regulate the level of sex hormones,lipid and glucose metabolism,improve the polycystic changes and improve clinical efficacy in treating PCOS of phlegm-dampness due to deficiency of the spleen syndrome.

关 键 词：五积散 脾虚痰湿型 多囊卵巢综合征 性激素 糖代谢 脂代谢 

分 类 号：R711.76[医药卫生—妇产科学]