中药膏剂外敷治疗外周静脉导管相关静脉炎的应用研究  

Study on topical application of traditional Chinese medicine plaster in the treatment of peripheral intravenous cathete-related phlebitis

作　　者：刘兰香 宋辉[2] 李兆军 何广云 张建国 王红 LIU Lanxiang;SONG Hui;LI Zhaojun;HE Guangyun;ZHANG Jianguo;WANG Hong(School of Nursing,Weifang Medical University,Weifang 261053,Shandong,China;Department of Science and Education,Gaomi People’s Hospital Affiliated to Weifang Medical University,Gaomi 261500,Shandong,China;Department of Pharmacy,Qingdao Huangdao District Hospital of Traditional Chinese Medicine,Qingdao 266400,Shandong,China;Department of Nursing,the First Affiliated Hospital of Shandong First Medical University,Jinan 250014,Shandong,China)

机构地区：[1]潍坊医学院护理学院,山东潍坊261053 [2]潍坊医学院附属高密市人民医院科教科,山东高密261500 [3]青岛市黄岛区中医医院药剂科,山东青岛266400 [4]山东第一医科大学第一附属医院护理部,山东济南250014

出　　处：《中国现代医生》2023年第31期86-89,共4页China Modern Doctor

基　　金：山东省潍坊市中医药科研计划项目(2021-4-144,2020-4-121)。

摘　　要：目的探讨中药膏剂外敷治疗外周静脉导管相关静脉炎的临床疗效。方法选取2022年3月至10月于潍坊医学院附属高密市人民医院住院治疗的静脉炎患者148例,根据随机数字表法将纳入患者分为对照组和治疗组,每组各74例。对照组患者使用50%硫酸镁溶液湿敷,治疗组患者使用中药膏剂外敷。比较两组患者治疗前后的C反应蛋白(C-reactive protein,CRP)、疼痛数字评分量表(numerical rating scale,NRS)评分。评价两组患者的临床疗效和治疗安全性。结果治疗组患者的痊愈率和总有效率均显著高于对照组(P<0.05);治疗组患者的痊愈时间显著短于对照组[(41.2±11.8)h vs.(61.5±14.6)h,t=7.950,P=0.007]。治疗后,两组患者的CRP水平、NRS评分均显著低于本组治疗前(P<0.05),且治疗组患者的CRP水平、NRS评分均显著低于对照组(P<0.05)。结论中药膏剂外敷治疗外周静脉导管相关静脉炎,能显著改善其临床症状,降低血清炎症因子水平,疗效确切。Objective To investigate the clinical effect of topical application of traditional Chinese medicine plaster on peripheral intravenous cathete-related phlebitis.Methods A total of 148 patients with phlebitis hospitalized in Gaomi People’s Hospital Affiliated to Weifang Medical University from March to October 2022 were selected and divided into control group and treatment group according to random number table method,with 74 cases in each group.The control group was wet compress with 50%magnesium sulfate solution,and the treatment group was topical application with traditional Chinese medicine plaster.C-reactive protein(CRP)and scores of numerical rating scale(NRS)before and after treatment were compared between the two groups.The clinical efficacy and treatment safety of the two groups were evaluated.Results The recovery rate and total effective rate of treatment group were significantly higher than those of control group(P<0.05).The recovery time of treatment group was significantly shorter than that of control group[(41.2±11.8)h vs.(61.5±14.6)h,t=7.950,P=0.007].After treatment,CRP level and NRS score in two groups were significantly lower than before treatment(P<0.05).The CRP level and NRS score in treatment group were significantly lower than those in control group(P<0.05).Conclusion The treatment of peripheral intravenous cathete-related phlebitis by topical application of traditional Chinese medicine plaster can significantly improve the clinical symptoms and reduce the level of serum inflammatory factors,and has a definite effect.

关 键 词：静脉穿刺 静脉炎 外周静脉导管 中药膏剂 

分 类 号：R543.6[医药卫生—心血管疾病]