内蒙古部分地区蒙古族居民高尿酸血症及痛风危险因素的研究分析  

The Analysis of Risk Factors for Hyperuricemia and Gout Among Mongolian Residents in Some Regions of Inner Mongolia

作　　者：高雅静 赵文娟 朱凌妍 郎名丽 平春玲 王永福[1] GAO Yajing;ZHAO Wenjuan;ZHU Lingyan;LANG Mingli;PING Chunling;WANG Yongfu(Department of Rheumatology,The First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou 014010 China;Department Geriatric Second,Inner Mongolia Xilingol League Central Hospital,Xilinghot 026000 China;Department Rheumatology and Immunology,Inner Mongolia Xilingol League Central Hospital,Xilinghot 026000 China)

机构地区：[1]内蒙古科技大学包头医学院第一附属医院风湿免疫科,内蒙古包头014010 [2]内蒙古锡林郭勒盟中心医院老年医学二科,内蒙古锡林浩特026000 [3]内蒙古锡林郭勒盟中心医院风湿免疫科,内蒙古锡林浩特026000

出　　处：《内蒙古医学杂志》2023年第9期1041-1045,1050,共6页Inner Mongolia Medical Journal

摘　　要：目的了解内蒙古部分地区蒙古族居民高尿酸血症及痛风的流行病学特征,分析影响蒙古族居民高尿酸血症及痛风患病率的危险因素。方法采用横断面调查研究,选取内蒙古部分地区三代内无与其他民族通婚的457名蒙古族居民作为研究对象,调查一般人口学特征、生活方式与饮食习惯及身体一般指标和生化指标,二元Logistic回归筛选危险因素。结果高尿酸血症人群中,蒙古族居民饮酒量高于汉族居民(P<0.05);痛风人群中,蒙古族居民饮酒量和食用动物内脏量高于汉族居民(P<0.05)。与血尿酸正常人群相比,男性、蒙古族居民饮酒及食用动物内脏的人群高尿酸血症的发生率更高,差异有统计学意义(P<0.05)。与无痛风人群相比,男性、蒙古族居民饮酒、睡眠质量差,合并有糖尿病、心血管疾病及高脂血症中任意一个病史的人群痛风的发病率更高。二元Logistic回归显示,男性、饮酒、食用动物内脏的蒙古族居民高尿酸血症风险增高(P<0.05);饮酒、睡眠质量差、合并糖尿病的蒙古族居民痛风风险增高(P<0.05)。结论内蒙古自治区蒙古族居民痛风和高尿酸血症的患病率相对较高,高尿酸血症和痛风人群中,蒙古族居民的饮酒量高于汉族居民,饮酒是蒙古族居民高尿酸血症和痛风的共同危险因素。Objective To understand the epidemiological characteristics of hyperuricemia and gout among Mongolian residents in some regions of Inner Mongolia and to analyze the risk factors affecting the prevalence of hyperuricemia and gout among Mongolian residents.Methods A cross-sectional survey study was conducted to select 457 Mongolian residents who had not intermarried with other ethnic groups within three generations in some areas of Inner Mongolia as the study population.General demographic characteristics,lifestyle and dietary habits,general physical indicators and biochemical indicators were investigated,and risk factors were screened by binary logistic regression.Results Mongolian residents drank more alcohol than Han residents to among those with hyperuricemia(P<0.05);Mongolian residents drank more alcohol and consumed more animal offal than Han residents among those with gout(P<0.05).Compared to those with normal blood uric acid,the prevalence of hyperuricemia was higher among men and Mongolian residents who consumed alcohol and animal offal,with a statistically significant difference(P<0.05).The incidence of gout was higher in men,Mongolian residents who drank alcohol,had poor sleep quality,and had a combined history of any of diabetes,cardiovascular disease and hyperlipidaemia compared to those without gout.Binary logistic regression showed that Mongolian residents who were male,drank alcohol,and consumed animal offal had an increased risk of hyperuricemia(P<0.05);those who drank alcohol,had poor sleep quality,and had combined diabetes had an increased risk of gout(P<0.05).Conclusion The prevalence of gout and hyperuricemia is relatively high among Mongolian residents in Inner Mongolia Autonomous Region.Among the population with hyperuricemia and gout,alcohol consumption is higher among Mongolian residents than Han Chinese residents,and alcohol consumption is a common risk factor for hyperuricemia and gout among Mongolian residents.

关 键 词：高尿酸血症 痛风 蒙古族 危险因素 

分 类 号：R589.7[医药卫生—内分泌]