急性下肢深静脉血栓患者股深静脉血栓形成与髂静脉血栓和肺栓塞的相关性研究  

Correlation study among profunda femoris vein thrombosis,iliac vein thrombosis and pulmonary embolism in patients with acute lower extremity deep vein thrombosis

作　　者：阿力清·阿布都萨拉木 哈力木拉提·木尔提扎[1] 赛力克·马高维亚[1] 哈尔满·阿吉汗[1] 买吐鲁佰·米尔扎合买提 Aliqing Abudusalamu;Halimulati Muertiza;Sailike Magaoweiya;Haerman Ajihan;Maitulubai Mierzahemaiti(Department of Vascular and Thyroid Surgery,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第一附属医院血管甲状腺外科,新疆乌鲁木齐830054

出　　处：《中国血管外科杂志（电子版）》2023年第3期243-247,共5页Chinese Journal of Vascular Surgery(Electronic Version)

摘　　要：目的研究急性下肢深静脉血栓形成(deep vein thrombosis,DVT)患者股深静脉血栓形成与发生髂静脉血栓及肺栓塞的相关性。方法回顾性分析新疆医科大学第一附属医院2018年1月至2022年6月收治的155例急性下肢DVT患者资料,根据有无累及股深静脉分成股深静脉血栓组和对照组,统计两组中累及同侧髂静脉和发生肺栓塞的患者,多因素Logistic回归分析股深静脉血栓是否为同侧髂静脉血栓以及肺栓塞的危险因素。结果股深静脉血栓是发生肺栓塞的危险因素(OR=3.780,95%CI=1.723~8.290,P=0.001)。男性(OR=4.051,95%CI=2.203~8.111,P<0.001)、下腔静脉血栓形成(OR=0.442,95%CI=0.198~0.986,P=0.046)、小腿静脉血栓形成(OR=2.363,95%CI=1.069~5.227,P=0.034)、腘静脉血栓形成(OR=2.542,95%CI=1.155~5.592,P=0.020)、红细胞计数≥4.13×10^(12)/L(OR=1.967,95%CI=1.025~3.777,P=0.042)、血红蛋白浓度≥128.5 g/L(OR=2.229,95%CI=1.164~4.266,P=0.016)、肌酐≤59.19μmol/L(OR=2.137,95%CI=1.116~4.094,P=0.022)是急性DVT患者发生肺栓塞的危险因素。结论急性下肢DVT患者股深静脉血栓形成与累及同侧髂静脉以及发生肺栓塞密切相关。Objective To study the correlation among profunda femoris vein thrombosis,iliac vein thrombosis and pulmonary embolism in patients with acute lower extremity deep vein thrombosis(DVT).Methods The data of 155 patients with acute lower extremity DVT admitted to the First Affiliated Hospital of Xinjiang Medical University from January 2018 to June 2022 were analyzed retrospectively.According to whether the profunda femoris vein was involved,they were divided into a profunda femoris vein thrombosis group and a control group,and patients with iliac vein and pulmonary embolism were calculated.Multivariate Logistic regression analysis was used to analyze whether profunda femoris vein thrombosis was a risk factor for ipsilateral iliac vein thrombosis and pulmonary embolism.Results Profunda femoris vein thrombosis was a risk factor for pulmonary embolism(OR=3.780,95%CI=1.723-8.290,P=0.001).Male(OR=4.051,95%CI=2.203~8.111,P<0.001),inferior vena cava thrombosis(OR=0.442,95%CI=0.198~0.986,P=0.046),calf vein thrombosis(OR=2.363,95%CI=1.069~5.227,P=0.034),popliteal vein thrombosis(OR=2.542,95%CI=1.155~5.592,P=0.020),red blood cell count≥4.13×10^(12)/L(OR=1.967,95%CI=1.025~3.777,P=0.042),hemoglobin≥128.5 g/L(OR=2.229,95%CI=1.164~4.266,P=0.016),creatinine≤59.19μmol/L(OR=2.137,95%CI=1.116~4.094,P=0.022)were the risk factors for pulmonary embolism in patients with acute DVT.Conclusion The profunda femoris vein thrombosis in patients with acute lower extremity DVT is closely related to the ipsilateral iliac vein and pulmonary embolism.

关 键 词：深静脉血栓形成 股深静脉 肺栓塞 LOGISTIC回归分析 

分 类 号：R543.6[医药卫生—心血管疾病] R563.5[医药卫生—内科学]