妊娠期糖尿病高危因素的相关研究进展  

Research Progress in High-risk Factors of Gestational Diabetes Mellitus

作　　者：徐飞飞 孙云秀 黄明莉[3] XU Feifei;SUN Yunxiu;HUANG Mingli(Department of Obstetrics,the First People′s Hospital of Suqian,Suqian 223800,China;Department of Delivery Room,Ji′nan Zhangqiu District People′s Hospital,Jinan 250200,China;Department of Obstetrics and Gynecology,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]宿迁市第一人民医院产科,江苏宿迁223800 [2]济南市章丘区人民医院产房,济南250200 [3]哈尔滨医科大学附属第一医院妇产科,哈尔滨150001

出　　处：《医学综述》2023年第2期353-357,共5页Medical Recapitulate

摘　　要：伴随孕前肥胖人数的增加及生活方式的改变,妊娠期糖尿病(GDM)的患病率在全球范围内有所增加,在新的诊断标准下患病率可能会更高。GDM的病因复杂多样,目前还没有完全明确。肥胖、高龄、糖尿病史或既往GDM病史是GDM已知公认的高危因素,多囊卵巢综合征、子痫前期、炎症因子和体内铁储备水平、肠道微生物群、种族和遗传易感性、抑郁和睡眠质量、环境污染物与GDM的发病也密切相关,但仍有其他因素存在争议。因此,未来需要对GDM的高危因素进行全面性的综合评估,以期对此类人群采取个性化的预防措施。With the increments in obesity before pregnancy and changes in lifestyles,the prevalence of gestational diabetes mellitus(GDM)has increased globally,which may be higher under the new diagnostic criteria.The etiology of GDM is complex and diverse and has not yet been fully understood.Obesity,advanced age,history of diabetes or previous history of GDM are known and recognized risk factors for GDM,while polycystic ovary syndrome,preeclampsia,inflammatory factors and iron storage levels in the body,gut microbiota,race and genetic susceptibility,depression and sleep quality,environmental pollutants are closely related to the onset of GDM,however,there are still other factors remaining controversial.Therefore,it is necessary to conduct a comprehensive assessment of the high-risk factors of GDM in order to take individualized preventive measures for such population.

关 键 词：妊娠期糖尿病 高危因素 预防 

分 类 号：R714.256[医药卫生—妇产科学]