骨关节炎的免疫发病机制及物理因子治疗研究进展  

Research Progress in Immunopathogenesis of Osteoarthritis and Physical Factor Therapy

作　　者：石艺 李雪萍[1] SHI Yi;LI Xueping(Department of Rehabilitation Medicine,Nanjing First Hospital/Nanjing Hospital,Nanjing Medical University,Nanjing 210006,China)

机构地区：[1]南京医科大学附属南京医院南京市第一医院康复医学科,南京210006

出　　处：《医学综述》2023年第3期417-423,共7页Medical Recapitulate

基　　金：国家自然科学基金(82072541)。

摘　　要：骨关节炎(OA)是一种常见的退行性骨关节疾病,临床表现为关节肿胀、疼痛等。随着人口老龄化程度逐渐加重,OA发病率及致残率显著增加,给个人和社会造成了严重的负担。免疫系统参与OA的发病过程,在OA的发生发展中扮演重要角色,为后续预防和治疗OA奠定了理论基础。物理因子治疗作为一种无创的治疗措施,可以通过减轻机体免疫炎症反应,缓解OA患者疼痛并改善关节功能。目前,基于免疫机制的物理因子治疗已经成为OA治疗的新方向。Osteoarthritis(OA)is a common degenerative bone and joint disease with clinical manifestations such as joint swelling and pain.With the gradual increase of population aging,the incidence and disability rate of OA have increased significantly,bringing a serious burden to the individuals and society.The immune system is involved in the pathogenesis of OA and plays an important role in the development of OA,which lays a theoretical basis for the subsequent prevention and treatment of OA.Physical factor therapy,as a non-invasive therapeutic measure,could relieve pain and improve joint function in the OA patients by reducing the immune inflammatory response of the body.Currently,physical factor therapy based on immune mechanisms has become a new direction in the treatment of OA.

关 键 词：骨关节炎 免疫机制 物理因子治疗 

分 类 号：R684.3[医药卫生—骨科学]